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(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid

Flunarizine dihydrochloride Struktur
30484-77-6
CAS-Nr.
30484-77-6
Bezeichnung:
(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid
Englisch Name:
Flunarizine dihydrochloride
Synonyma:
FLUNARIZINE HCL;FLUNARIZINE HYDROCHLORIDE;Gradient;Flunarizine dihydrochloride CRS;Mondus;Issium;r14950;Flunarl;kw-3149;Flunagen
CBNumber:
CB2377940
Summenformel:
C26H28Cl2F2N2
Molgewicht:
477.42
MOL-Datei:
30484-77-6.mol
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(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Eigenschaften

Schmelzpunkt:
188-190?C
storage temp. 
2-8°C
Löslichkeit
chloroform/methanol (9:1): 50 mg/mL, clear, colorless
Farbe
White to Off-White
Merck 
13,4170
BRN 
4284243
CAS Datenbank
30484-77-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 22
WGK Germany  3
RTECS-Nr. TK9187000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.

Chemische Eigenschaften

White Solid

Verwenden

Flunarizine dihydrochloride has been used to study the effect of flunarizine on epileptiform activity. It is also used to study its effect on high-potassium induced increase of intracellular free calcium.

Allgemeine Beschreibung

Flunarizine has antihistamine, anticonvulsant and vestibular depressive properties. It protects endothelial cells from calcium overload-induced damage. Flunarizine is used to treat epilepsy, migraine prophylaxis, cerebral blood flow disturbances, peripheral vascular disease and vertigo.

Biologische Aktivität

Dual Na + /Ca 2+ channel blocker; a cerebral and peripheral vasodilator. Neuroprotective.

(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Fluorbenzol Zimtalkohol Piperazin Fluoroboric acid 4,4'-Diamino-diphenyl-methan Natriumcarbonat 1-Cinnamylpiperazin

Downstream Produkte

(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 381)Lieferanten
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30484-77-6((E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid)Verwandte Suche:

Kresoxim-methyl Methylacrylat Natrium-2-methylprop-2-en-1-sulfonat Methacryloylchlorid Flunarizin 1-Methylpiperazin 2,3-Diphenylcycloprop-2-en-1-on N,N'-Methylendiacrylamid Methylacrylaldehyd Methyl-4-hydroxybenzoat Phenylvalerat Thiophanat-methyl Piperazin Bensulfuron methyl Rimantadine Methyl Dihydrochloride Tetryzolinhydrochlorid
  • Flugeral
  • Flunarl
  • Fluxarten
  • Issium
  • Flunarizine dihydrochloride,1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
  • Flunarizine-d8 dihydrochloride
  • 1-[Bis(4-fluorophenyl)Methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine Hydrochloride
  • Dinaplex
  • Flunagen
  • Mondus
  • Flunarizine Dihydrochloride (EP/BP)
  • Piperazine,1-[bis(4-fluorophenyl)Methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2)
  • 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-piperazine,hydrochloride (1:2)
  • (e)-1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)piperazinedihydroch
  • 1-(BIS[4-FLUOROPHENYL]) DIHYDROCHLORIDE
  • 1-[BIS(4-FLUOROPHENYL)METHYL]-4-(3-PHENYL-2-PROPENYL)PIPERAZINE 2 HCL
  • 1-[BIS(4-FLUOROPHENYL)METHYL]-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLO RIDE
  • (e)-1-(bis(p-fluorophenyl)methyl)-4-cinnamylpiperazinedihydrochloride
  • 1-(bis(p-fluorophenyl)methyl)-4-cinnamyl-,dihydrochloride,(e)-piperazin
  • kw-3149
  • r14950
  • (E)-1-[BIS(4-FLUOROPHENYL)METHYL]-4-(3-PHENYL-2-PROPENYL)PIPERAZINE DIHYDROCHLORIDE
  • FLUNARIZINE 2HCL
  • FLUNARIZINE DIHYDROCHLORIDE
  • Flunarizine, DiHCl
  • (E)-1-[bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine dihydrochloride
  • FLUNARIZINE DIHYDROCHLORIDE CA2+/NA+ CHA NNEL ANTA
  • FLUNARIZIN-DIHYDROCHLORIDE
  • FLUNARIZINE HYDROCHLORIDE EPF(CRM STANDARD)
  • 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine dihydrochloride
  • Flunarizine dihydrochloride for system suitability CRS
  • Flunarizine dihydrochloride USP/EP/BP
  • Flunarizine dihydrochloride for system suitability (Y0000266)
  • Flunarizine dihydrochloride CRS
  • FLUNARIZINE HYDROCHLORIDE
  • FLUNARIZINE HCL
  • Gradient
  • 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine dihydrochloride
  • FLURIZINE EP IMPURITY D
  • 30484-77-6
  • 30784-77-6
  • 30848-77-6
  • C26H26F2N22HCl
  • C26H26F2N22ClH
  • C26H28Cl2F2N2
  • C26H28F2N2
  • 47742
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  • Voltage-gated Ion Channels
  • BioChemical
  • Cell Signaling and Neuroscience
  • Calcium Channel Modulators
  • Cell Biology
  • Analytical Chromatography Product Catalog
  • Inhibitors and Activators
  • Ion Channels
  • Analytical Standards
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