Virginiamycin M1
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- CAS-Nr.
- 21411-53-0
- Bezeichnung:
- Virginiamycin M1
- Englisch Name:
- VIRGINIAMYCIN M1
- Synonyma:
- Streptogramin A;C11299;PA 114A;Factor M;NSC 87432;NSC 244426;MIKAMYCIN A;Vernamycin A;STAPHYLOMYCIN;AVirginiaMyci
- CBNumber:
- CB3294594
- Summenformel:
- C28H35N3O7
- Molgewicht:
- 525.59
- MOL-Datei:
- 21411-53-0.mol
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Virginiamycin M1 Eigenschaften
- Schmelzpunkt:
- 165-167℃
- alpha
- D20 -218° ( c = 0.34 in ethanol)
- Siedepunkt:
- 825.2±65.0 °C(Predicted)
- Dichte
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Löslichkeit
- chloroform/methanol: soluble10mg/mL
- Aggregatzustand
- powder
- pka
- 13.18±0.70(Predicted)
- Farbe
- yellow to tan
- Stabilität:
- Light Sensitive
Virginiamycin M1 Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Light yellow powder
Verwenden
Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA.
Definition
ChEBI: A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms includ
ng methicillin-resistant Staphylococcus aureus.
Kontakt-Allergie
Like the other streptogramin, pristinamycin, virginiamycin
is made of two subunits, virginiamycin S1 and
virginiamycin M1. Dermatitis was quite common in
people using the formerly available topical virginiamycin.
Occupational dermatitis was observed in the
pharmaceutical industry, in breeders, and in a surgeon
who used topical virginiamycin on postoperative
wounds (personal observation).
Virginiamycin M1 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Virginiamycin M1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 100)Lieferanten
21411-53-0(Virginiamycin M1)Verwandte Suche:
- C11299
- MikamycinA, Staphylomycin
- Antibiotic PA-114A1
- Pristinamycin IIA
- Staphylomycin M1
- Vernamycin A
- VirginiaMycin M1
DISCONTINUED
- MIKAMYCIN A
- STAPHYLOMYCIN
- VIRGINIAMYCINE
- VIRGINIAMYCIN M1
- (3R,4R,5E,10E,12E,14S)-
- VirginiaMycin M1 (90%)
- AVirginiaMyci
- MikaMycin A, PristinaMycin IIA, StephyloMycin M1, StreptograMin A, Syncothrecin A, Synergistin A1, VirginiaMycin M1, VernaMycin A, 14752-2, E129A, PA 114A, 1745Z3A, 547C, Factor M
- Ostreogrycin A
- VirginiaMycin M1, froM StreptoMyces virginiae
- Antibiotic PA 114A
- Factor M
- Factor M (antibiotic)
- NSC 244426
- NSC 87432
- PA 114A
- Pristinamycin II
- Verginiamycin M1 Ostreogrycin A Antibiotic PA 114A NSC 244426 NSC 87432
- Virginiamycin M1, 98%, from Streptomyces virginiae
- 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S)-
- Virginiamycin M1 Solution in Methanol,1000ug/ml
- Pristinamycin IIAQ: What is
Pristinamycin IIA Q: What is the CAS Number of
Pristinamycin IIA Q: What is the storage condition of
Pristinamycin IIA Q: What are the applications of
Pristinamycin IIA
- Streptogramin A
- Pristinamycin ⅡA
- Pristinamycin ⅡA
- Lepidophorin A
- 21411-53-0
- C28H35N3O7
- Antibiotics A to Z
- Antibiotics
- Antibiotics T-Z
- BioChemical
- antibiotic
- Chiral Reagents
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
