marcfortine A

75731-43-0

CAS-Nr.: 75731-43-0

Englisch Name:: marcfortine A

Synonyma:: UK 111866;marcfortine A;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)-

CBNumber:: CB41323193

Summenformel:: C28H35N3O4

Molgewicht:: 477.602

MOL-Datei:: 75731-43-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 16

marcfortine A Eigenschaften

Schmelzpunkt:: 245 °C

Siedepunkt:: 660.6±55.0 °C(Predicted)

Dichte: 1.33±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: Methanol: soluble

Aggregatzustand: A solid

pka: 12.05±0.60(Predicted)

Sicherheit

marcfortine A Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD₉₉ = 0.06 μg/ml) and inhibits motility of adult worms (EC₅₀ = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED₉₅s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α₃ subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.

Verwenden

Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission.

marcfortine A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

marcfortine A Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 16)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55936	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8864	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.com	China	24246	58

75731-43-0()Verwandte Suche:

2-(3,4-Dihydroxyphenyl)valeramid

marcfortine A
UK 111866
Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)-
75731-43-0