KD 5170

940943-37-3

CAS-Nr.: 940943-37-3

Englisch Name:: KD 5170

Synonyma:: KD 5170;KD5170; KD-5170;S-(2-(6-(4-(3-(DiMethylaMino)propoxy)phenylsulfonaMido)pyridin-3-yl)-2-oxoethyl) ethanethioate;S-(2-{6-[({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p Yridinyl}-2-oxoethyl) Ethanethioate;Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester

CBNumber:: CB42538280

Summenformel:: C20H25N3O5S2

Molgewicht:: 451.56

MOL-Datei:: 940943-37-3.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 48

KD 5170 Eigenschaften

Siedepunkt:: 637.9±65.0 °C(Predicted)

Dichte: 1.310±0.06 g/cm3(Predicted)

storage temp.: Sealed in dry,Room Temperature

Löslichkeit: ≥21.2 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH

Aggregatzustand: solid

pka: 9.29±0.28(Predicted)

Sicherheit

KD 5170 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

KD 5170 is a mercaptoketone-based inhibitor of class I and II histone deacetylases (HDACs; IC₅₀s = 20, 2,060, 75, 26, 950, 14, 85, 2,500, 150, and 18 nM for HDAC1-10, respectively). It exhibits broad spectrum antitumor activity in vitro and in vivo. KD 5170 increases the acetylation of histones and activates caspases 3, 8, and 9, leading to apoptosis in primary myeloma cells.

KD 5170 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

KD 5170 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 48)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Sichuan Biosynce Pharmatech Co., Ltd.	+8619950309693	diane@biosynce.com	China	4874	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.	028-85114309 15881143215	liangli@happysyn.com	China	1734	55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66099280 17798518460	cfzhang@aikonchem.com	China	19918	55
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58

KD 5170
S-(2-(6-(4-(3-(DiMethylaMino)propoxy)phenylsulfonaMido)pyridin-3-yl)-2-oxoethyl) ethanethioate
KD5170; KD-5170
S-(2-{6-[({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p Yridinyl}-2-oxoethyl) Ethanethioate
Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester
940943-37-3