N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethandiamin-monohydrochlorid
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- CAS-Nr.
- 135-23-9
- Bezeichnung:
- N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethandiamin-monohydrochlorid
- Englisch Name:
- METHAPYRILENE HYDROCHLORIDE
- Synonyma:
- dozar;barhist;coryzol;blueline;capathyn;histafed;methacon;Cohistine;somnicaps;methoxylene
- CBNumber:
- CB4405690
- Summenformel:
- C14H20ClN3S
- Molgewicht:
- 297.85
- MOL-Datei:
- 135-23-9.mol
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N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethandiamin-monohydrochlorid Eigenschaften
- Schmelzpunkt:
- 162°
- storage temp.
- room temp
- Löslichkeit
- DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
- Stabilität:
- Hygroscopic
- EPA chemische Informationen
- Methapyrilene hydrochloride (135-23-9)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
T |
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| R-Sätze: |
25 |
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| S-Sätze: |
22-36-45 |
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| RIDADR |
UN 2811 6.1/PG 3 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
UT1750000 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| Toxizität |
LD50 oral in rat: 200mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethandiamin-monohydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Verwenden
Methapyrilene is used as antihistaminic agent.
Definition
ChEBI: A hydrochloride that is the monohydrochloride salt of methapyrilene.
Allgemeine Beschreibung
Methapyrilene hydrochloride,2-[[2-(dimethylamino)-ethyl]-2-thienylarnino]pyridine monohydrochloride (Histadyl) is available as the bitter-tasting, white crystalline powder that is soluble in water(1:0.5), in alcohol (1:5), and in chloroform (1:3). Its solutionshave a pH of about 5.5. It differs structurally from tripelennaminein having a 2-thiophene—methylene group in placeof the benzyl group. The thiophene ring is considered isostericwith the benzene ring, and the isosteres exhibit similaractivity. A study of the solid-state conformation of methapyrilenehydrochloride showed that the trans-conformation is preferredfor the two ethylenediamine nitrogen atoms. The Foodand Drug Administration declared methapyrilene a potentialcarcinogen in 1979, and all products containing it have beenrecalled.
Air & Water Reaktionen
Water soluble.
Reaktivität anzeigen
METHAPYRILENE HYDROCHLORIDE is light sensitive. Solutions of METHAPYRILENE HYDROCHLORIDE in water, DMSO, 95% ethanol or acetone should be stable for 24 hours under normal lab conditions. . Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas.
Brandgefahr
Flash point data for METHAPYRILENE HYDROCHLORIDE are not available; however, METHAPYRILENE HYDROCHLORIDE is probably combustible.
N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethandiamin-monohydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethandiamin-monohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 33)Lieferanten
135-23-9(N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethandiamin-monohydrochlorid)Verwandte Suche:
- N,N-DIMETHYL-N'-[2-PYRIDINYL]-N'-[2-THIENYLMETHYL]-1,2-ETHANEDIAMINE HYDROCHLORIDE
- 2-((2-(dimethylamino)ethyl)-2-thenyl-amino)pyridinehydrochloride
- 2-((2-(dimethylamino)ethyl)-2-thenylamino)-pyridinmonohydrochloride
- METHAPYRILENE HCL
- METHAPYRILENE HYDROCHLORIDE
- LABOTEST-BB LT00772145
- 2-dimethylaminoethyl-(2-pyridyl)-(2-thenyl)amine hydrochloride
- N',N'-dimethyl-N-pyridin-2-yl-N-(thiophen-2-ylmethyl)ethane-1,2-diamine hydrochloride
- Cohistine
- N,N-DiMethyl-N'-2-pyridinyl-N'-(2-thienylMethyl)-1,2-ethanediaMine MonoHydrochloride
- N1,N1-DiMethyl-N2-2-pyridinyl-N2-(2-thienylMethyl)-1,2-ethanediaMine Hydrochloride
- 2-ethanediamine,n,n-dimethyl-n’-2-pyridinyl-n’-(2-thienylmethyl)-monohyd
- 2-ethanediamine,n,n-dimethyl-n’-2-pyridinyl-n’-(2-thienylmethyl)-monohydro
- barhist
- blueline
- capathyn
- compound01013
- coryzol
- dozar
- histafed
- methacon
- methoxylene
- n,n-dimethyl-n’-(2-pyridyl)-n’-(2-thenyl)ethylenediaminehydrochloride
- n,n-dimethyl-n’-(2-pyridyl)-n’-(2-thenyl)-ethylenediaminhydrochloride
- n,n-dimethyl-n’-(2-thenyl)-n’-(2-pyridyl-ethylene-diaminehydrochloride)
- semikonhydrochloride
- somnicaps
- tem-histine
- thenylenehydrochloride
- thenylpyraminehydrochloride
- w-53hydrochloride
- METHAPYRILENE HCL, 1000MG,NEAT
- Zavegepant Impurity 10
- 135-23-9
- C14H19N3SHCl
- C14H19N3SClH
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Sulfur & Selenium Compounds
- Alpha Sort
- M
- MAlphabetic
- META - METH
- Volatiles/ Semivolatiles
