Thiophen-2-ethylamin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
A colorless to yellow liquid with unstable properties requiring protection with nitrogen gas. It appears as a light yellow clear liquid, but turns red upon prolonged exposure.
Verwenden
[2-(Thiophene-2-yl)ethyl]amine is used in the synthesis of geldanamycin derivatives as HCV replication inhibitors targetting Hsp90.
Allgemeine Beschreibung
2-Thiopheneethylamine (2-(thiophen-2-yl)ethanamine) is an aromatic amine. It undergoes microwave induced condensation with iminodiacetic acid to form the corresponding piperazine-2,6-dione derivatives. Its effect as a probable substitute to the pyridine ligand on the performance of poly(3-hexylthiophene)/CdSe hybrid solar cells has been investigated.
Einzelnachweise
[1] M. BARWIOLEK. Structural and spectral studies of silver(I) complexes with new Schiff bases derived from 2-thiopheneethylamine and their application in thin layer deposition by spin and dip coating techniques[J]. Polyhedron, 2017, 124: Pages 12-21. DOI:
10.1016/j.poly.2016.12.011.
[2] BHUSHAN D. VARPE S B J. Schiff Base of Isatin with 2-Thiopheneethylamine and Its Mannich Bases: Synthesis, Docking, and In Vitro Anti-Inflammatory and Antitubercular Activity[J]. Russian Journal of Bioorganic Chemistry, 2022, 48 2: 372-379. DOI:
10.1134/S1068162022020030.
[3] JUN YAN LEK. Understanding the Effect of Surface Chemistry on Charge Generation and Transport in Poly (3-hexylthiophene)/CdSe Hybrid Solar Cells[J]. ACS Applied Materials & Interfaces, 2011, 3 2: 287-292. DOI:
10.1021/am100938f.
[4] SANDEEP KUMAR. Efficient synthesis of piperazine-2,6-dione and 4-(1H-indole-2-carbonyl)piperazine-2,6-dione derivatives and their evaluation for anticancer activity[J]. Medicinal Chemistry Research, 2013, 22 10: 4600-4609. DOI:
10.1007/s00044-012-0438-7.
Thiophen-2-ethylamin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4,5,6,7-Tetrahydrothieno[3,2,c] pyridine hydrochloride
5-(2-AMINOETHYL)THIOPHENE-2-SULFONAMIDE
Clopidogrel hydrogen sulfate
5,6,7,7a-Tetrahydro-5-(triphenylmethyl)thieno[3,2-c]pyridinone
2-Thienylacetonitril
Thieno[3,2-c]pyridine, 4-(5-chloro-2-thienyl)-4,5,6,7-tetrahydro-
