Fendilin

Fendiline Struktur
13042-18-7
CAS-Nr.
13042-18-7
Bezeichnung:
Fendilin
Englisch Name:
Fendiline
Synonyma:
N-(1-Phenylethyl)-3,3-diphenylpropylamine;3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-
CBNumber:
CB4874928
Summenformel:
C23H25N
Molgewicht:
315.45
MOL-Datei:
13042-18-7.mol

Fendilin Eigenschaften

Siedepunkt:
bp0.3 206-210°
Dichte
1.031±0.06 g/cm3(Predicted)
pka
9.49±0.28(Predicted)
Wasserlöslichkeit
2.331mg/L(22.5 ºC)

Sicherheit

Fendilin Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Sensit,Thiemann,W. Germany,1974

Manufacturing Process

21.13 grams of γ,γ-diphenyl-propylamine and 12.01 grams of acetophenone are hydrogenated in 200 ml of methanol at 55°C and a pressure of 10 atmospheres in the presence of palladium charcoal. On filtration of the catalyst the solution is concentrated and the remainder is distilled in vacuo at a pressure of 0.3 Hg mm. The main distillate is collected at 206° to 210°C. 25.38 grams of N-[1'-phenylethyl-(1')]-1,1-diphenyl-propyl-(3)-amine are obtained.
The product is dissolved in 134 ml of 96% ethanol whereupon 26.8 ml of concentrated hydrochloric acid and 201 ml of water are added while cooling with ice-water. The precipitate is filtered off and dried in vacuo at 100°C. 22.98 grams of N-[1'-phenylethyl)-(1')]-1,1-diphenyl-propyl-(3)-amine hydrochloride are obtained. MP 200° to 201°C. On recrystallization from 285 ml of a 2:1 mixture of water and 96% ethanol the melting point remains unchanged.

Therapeutic Function

Coronary vasodilator

Fendilin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Fendilin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 8)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63711 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923
1026@dideu.com China 9020 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.com China 24246 58

13042-18-7(Fendilin)Verwandte Suche:


  • N-(1-Phenylethyl)-3,3-diphenylpropylamine
  • 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine
  • Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-
  • 13042-18-7
  • C23H25N
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