(3R,3'S,5'R)-3,3'-Dihydroxy-β,K-carotin-6'-on Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Capsanthin is a carotenoid that has been found in
C. annuum and has diverse biological activities. It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and phosphorylation of ERK and p38 and prevents hydrogen peroxide-induced inhibition of gap junction intercellular communication in WB-F344 rat liver epithelial cells. Capsanthin (0.2 mg/animal) reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis. It also reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA; ).
Verwenden
Capsanthin may be used as an analytical reference standard for the quantification of the analyte in red pepper powder, red pepper fruits, paprika and oleoresin using chromatography techniques.
Allgemeine Beschreibung
Capsanthin, also known as the red pepper carotenoid, is one of the major color pigments of paprika oleoresin, an oil-soluble extract, isolated from the fruits of
Capsicum annum Linn or
Capsicum frutescens. It is widely used as a color additive in food industries across the globe. The photoprotective effect of capsanthin protects human dermal fibroblasts against UVB induced DNA damage.
Hazard
A poison by skin contact.
Sicherheitsprofil
A poison by skin
contact. When heated to decomposition it
emits acrid smoke and irritating vapors.
läuterung methode
Possible impurities are zeaxanthin and capsorubin (below). Purify capsanthin by chromatography on a column of alumina (grade IV) and develop with 0.2% EtOH in *C6H6. It
(3R,3'S,5'R)-3,3'-Dihydroxy-β,K-carotin-6'-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
