N,N-Dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-1,2-ethandiamin Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White, bitter, crystalline powder. Solutions
are acid to litmus.Soluble in water
and alcohol; very slightly soluble in ether; practically
insoluble in chloroform and benzene; 1%
solution in water has a pH of 4.3.
Verwenden
This drug lessens the allergic response of the organism caused by histamine. Tripelennamine
is used for allergic symptoms, rhinitis, conjunctivitis, and for allergic and anaphylactic reactions.
Synonyms of this drug are pelanin and pyribenzamine.
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Tripelennamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
SYMPTOMS: Symptoms of exposure to Tripelennamine may include euphoria, aplastic anemia, excitement, hallucinations, ataxia, incoordination, athetosis, convulsions, postictal depression, dry mouth, fixed dilated pupils, flushing of the face, fever, central nervous system depression, drowsiness and coma.
Brandgefahr
Flash point data for Tripelennamine are not available. Tripelennamine is probably combustible.
Sicherheitsprofil
Poison by ingestion and
intraperitoneal routes. Human mutation data
reported. Has been implicated in aplastic
anemia. Used as an antdustasnine. Addicts
have added it to paregoric to make "blue
velvet," whtch can cause euphoria by
injection. When heated to decomposition it
emits toxic fumes of NOx.
Stoffwechselwegen
When pyribenzamine is
incubated with rat liver microsomes, it is metabolized via N-oxide formation and
N-dealkylation which includes removal of the
dimethylamino moiety, the thiophenylmethyl moiety of
methaphenilene, and the benzyl moiety of
pyribenzamine.
N,N-Dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-1,2-ethandiamin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
