Xylazin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Xylazine is an agonist of α
2-adrenergic receptors (K
i = 194 nM). It is an analog of clonidine, an α
2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals. This product is also available as an analytical reference standard .
Verwenden
Xylazine is an α2 class of adrenergic receptor agonist. Xylazine is a clonidine analoque that acts on presynaptic and postsynaptic receptors as an a 2-adrenergic agonist.
Allgemeine Beschreibung
Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions.
Mechanism of action
Xylazine is marketed as its hydrochloride salt as Rompun (100 mg/mL) and
Anased (20 mg/mL) injectable solutions for intravenous administration to horses and dogs, respectively. The actions of xylazine may be reversed by the administration of yohimbine, an
indolalkylamine alkaloid, that blocks those α2-
adrenoreceptors that are stimulated by xylazine.
Nebenwirkungen
High doses of Xylazine can cause dizziness, vomiting, high blood sugar, blurry vision and even overdose deaths. If you inject xylazine into your body, you also may develop skin ulcers and severe wounds that can spread and worsen quickly.
Xylazine can lead to depression of the central nervous system along with other adverse effects. As for animals, they may show profound salivation following an injection with xylazine. Other adverse effects for dogs and cats include: muscle tremors, bradycardia with AV-block, hypotension, reduced respiratory rate, movement in response to strong auditory stimuli, and increased urination in cats.
Sicherheitsprofil
Poison by ingestion,
subcutaneous, and intravenous routes.
Human systemic effects: change in motor
activity, fall in blood pressure, miosis,
pleural thickening, pulse rate decrease,
somnolence. When heated to decomposition
it emits very toxic fumes of NOx and SOx.
Xylazin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
