SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Sibutramine was introduced as Meridia in the US for the control of obesity, in conjunction with a reduced-calorie diet. Sibutramine can be prepared in four steps from 4-chlorobenzyl cyanide. Sibutramine acts as a serotonin and noradrenaline reuptake inhibitor ; in animal studies, it reduces energy intake by creating a satieted feeling and increases energy expenditure by enhancing thermogenesis. In a clinical study in obese patients treated with 10 or 15 mg of Sibutramine once-daily, meaningful weight loss was sustained for 12 months ; an additional study demonstrated a lack of abuse potential. An appreciable part of Sibutramine's effect would also be due to its 2N-mono and didesmethylmetabolites, which are very potent monoamine reuptake inhibitors themselves.

Chemische Eigenschaften

White Solid

Verwenden

A serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

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• [1-[1-(4-chlorophenyl)cyclobutyl]-3-methyl-butyl]-dimethyl-amine hydrate hydrochloride
• 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine hydrate hydrochloride
• 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrate hydrochloride
• 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate
• Sibutramine Hydrochloride CIV (125 mg)
• )-SibutraMine-d6 HCl H2O
• 1-(4-Chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride
• CyclobutaneMethanaMine,1-(4-chlorophenyl)-N,N-diMethyl-a-(2-Methylpropyl)-, hydrochloride, hydrate (1:1:1)
• Sibutramine hydrochloride solution
• SibutramineHClH2O
• BTS-54524, Reductil, Meridia
• Meridia, Reductil, 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine monohydrate hydrochloride
• Sibutramine monohydrate hydrochloride
• SIBUTRAMINE HCL HYDRATE
• SIBUTRAMINE HYDROCHLORIDE HYDRATE
• SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
• 1-(1-(4-chlorophenyl)cyclobutyl)-N,N,3-trimethylbutan-1-amine hydrochloride hydrate
• Sibutramine sib
• Sibutramine Hydrochloride Monohydrate Standard
• Sibutramine Hydrochloride Monohydra
• Sibutramine hydrochloride solution in Methanol，1000ug/ml
• Sibutramine Hydrochloride MonohydrateQ: What is Sibutramine Hydrochloride Monohydrate Q: What is the CAS Number of Sibutramine Hydrochloride Monohydrate Q: What is the storage condition of Sibutramine Hydrochloride Monohydrate Q: What are the applications of Sibutramine Hydrochloride Monohydrate
• Sibutramine Hydrochloride CIV (1612845)
• SIBUTRAMINE HCL MONOHYDRATE
• 125494-59-9
• C17H19D7ClNHCl
• C17H26ClNxHClxH2O
• C16H24ClNHCl
• C17H26ClNHClH2O
• 33432
• CRESTOR
• Intermediates & Fine Chemicals
• Pharmaceuticals
• Anilines, Aromatic Amines and Nitro Compounds