Elamipretide

Elamipretide Struktur
736992-21-5
CAS-Nr.
736992-21-5
Englisch Name:
Elamipretide
Synonyma:
MTP-131;Centanafadine;SS-31, Elamipretide;Elamipretide acetate;RX-31;SS-31);Bendavia);Elamipretide;ELAMIPRETIDE, >99%;Elamipretide (SS-31
CBNumber:
CB92708860
Summenformel:
C32H49N9O5
Molgewicht:
639.79
MOL-Datei:
736992-21-5.mol

Elamipretide Eigenschaften

Dichte
1.34±0.1 g/cm3(Predicted)
Löslichkeit
Methanol (Slightly), Water (Slightly)
pka
10.10±0.25(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Sequenz
H-d-Arg-dimethylTyr-Lys-Phe-NH2
Stabilität:
Hygroscopic
InChIKey
SFVLTCAESLKEHH-WKAQUBQDSA-N
SMILES
C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N

Sicherheit

Elamipretide Chemische Eigenschaften,Einsatz,Produktion Methoden

Mechanism of action

Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.

Clinical Use

Barth syndrome is an ultra-rare genetic condition characterized by cardiac abnormalities leading to exercise intolerance, muscle weakness, debilitating fatigue, heart failure, recurrent infections, and delayed growth. There are currently no FDA- or EMA-approved therapies for patients with Barth syndrome. Elamipretide has an Orphan Drug, Fast Track and Rare Pediatric Designation from the FDA and Orphan Drug Designation from the EMA for treating Barth syndrome.

Nebenwirkungen

Side effects of elamipretide include:
Mild redness or itching at the injection site
Headache
Dizziness

Elamipretide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Elamipretide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 116)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Apeloa production Co.,Limited
+8619933239880
admin@apcl.com.cn China 323 58
Shandong Huisheng Import & Export Co., Ltd.
+86-13176845580 +86-13176845580
da@zhongda-biotech.com China 248 58
ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
+8619155187336
shengzhikai3@shengzhikai.com China 38 58
Zhejiang Hangyu API Co., Ltd
+8617531972939
anna@api-made.com China 2944 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177
sarah@tnjone.com China 1142 58
Qingdao Xinli Technology Development Co., Ltd.
+8616632313095
xinlikeji01@qdxlchem.com China 59 58
Shanghai Affida new material science and technology center
+undefined15081010295
admin@oudaxin.com China 399 58
Shanghai Chinqesen Biotechnology Co., Ltd.
+86-16628886292 +86-19521323435
sales2@qschem-pharma.com China 46 58
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139
admin@china-yime.com China 563 58
Shanghai Yunao International Trade Co., Ltd
+8617621705551
asdf@shanghaihg.cn China 265 58

736992-21-5()Verwandte Suche:


  • D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide
  • L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-
  • Elamipretide
  • Elamipretide (TFA salt)
  • SS-31;MTP-131;BENDAVIA
  • Bendavia)
  • Elamipretide (SS-31
  • ELAMIPRETIDE, >99%
  • Elamipretide,MTP-131,RX-31,SS-31, >99%
  • Elamipretide (MTP-131
  • ELAMIPRETIDE (MTP-131;RX-31;SS-31)
  • RX-31
  • SS-31)
  • Elamipretide (SS-31) acetate
  • (S)-6-Amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide
  • Elamipretide(HY-P0125
  • Centanafadine
  • MTP-131
  • SS-31, Elamipretide
  • Elamipretide acetate
  • Elamipretide、SS-31、H2N-D-Arg-Dmt-Lys-Phe-NH2
  • 736992-21-5
  • 736992-21-5
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