Diphenhydramine Hcl
- CAS No.
- 147-24-0
- Chemical Name:
- Diphenhydramine Hcl
- Synonyms
- DIPHENHYDRAMINE HCL;BAX;Benylin;Diphenhydramine HCI;Actifed;Ambenyl;Benacine;DIMEDROLUM;component of Caladryl;BENZHYDRAMINE HYDROCHLORIDE
- CBNumber:
- CB00130539
- Molecular Formula:
- C17H22ClNO
- Molecular Weight:
- 291.82
- MDL Number:
- MFCD00012479
- MOL File:
- 147-24-0.mol
- MSDS File:
- SDS
| Melting point | 168-172 °C |
|---|---|
| Boiling point | 163-167 °C(Press: 3 Torr) |
| Density | 1.0489 (rough estimate) |
| refractive index | 1.5800 (estimate) |
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | Very soluble in water, freely soluble in alcohol. |
| form | Crystalline Powder or Adhering Crystals |
| color | White |
| PH | pH(100g/L, 25℃) 4.0～5.5 |
| Water Solubility | 1000 g/L |
| Sensitive | Light Sensitive |
| Merck | 14,3309 |
| Stability | Stable, but slowly darkens upon exposure to light. Incompatible with strong oxidizing agents. |
| InChIKey | PCHPORCSPXIHLZ-UHFFFAOYSA-N |
| LogP | 3.662 (est) |
| FDA 21 CFR | 310.545; 336.10; 338.10; 341.12; 341.14 |
| CAS DataBase Reference | 147-24-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | TC2D6JAD40 |
| NCI Drug Dictionary | diphenhydramine hydrochloride |
| NIST Chemistry Reference | diphenhydramine hydrochloride(147-24-0) |
| EPA Substance Registry System | Diphenhydramine hydrochloride (147-24-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 36-45-36/37-16-7-24/25 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | KR7000000 | |||||||||
| HS Code | 29221990 | |||||||||
| Toxicity | LD50 orally in rats: 500 mg/kg (Gruhzit, Fisken) | |||||||||
| NFPA 704 |
|
Diphenhydramine Hcl price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D3630 | Diphenhydramine hydrochloride ≥98% (HPLC) | 147-24-0 | 5g | $47.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | D-015 | Diphenhydramine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 147-24-0 | 1mL | $26.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP896 | Diphenhydramine hydrochloride British Pharmacopoeia (BP) Reference Standard | 147-24-0 | 100MG | $262 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1218005 | Diphenhydramine hydrochloride United States Pharmacopeia (USP) Reference Standard | 147-24-0 | 200mg | $436 | 2024-03-01 | Buy |
| TCI Chemical | D0423 | Diphenhydramine Hydrochloride >98.0%(HPLC)(T) | 147-24-0 | 25g | $36 | 2024-03-01 | Buy |
Diphenhydramine Hcl Chemical Properties,Uses,Production
Uses
Diphenhydramine Hcl is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. It is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine Hcl is also used to prevent and treat motion sickness, and to treat insomnia (difficulty falling asleep or staying asleep). It is also used to control abnormal movements in people who have early stage parkinsonian syndrome (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) or who are experiencing movement problems as a side effect of a medication.
Side effects
Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Drug interactions
Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray).
Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, chlorpheniramine).
Dosage
Take the tablet, capsule, or liquid form by mouth with or without food. Measure liquid forms of this medication using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If you have a single-dose form of this medication (such as a single-use whistle), you do not need to measure the dose.
The rapidly-dissolving tablet or strip should be allowed to dissolve on the tongue and then swallowed, with or without water. The chewable tablets should be chewed thoroughly before being swallowed.
Diphenhydramine Hcl Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2996 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18444 | 58 |
| Guangzhou Tengyue Chemical Co., Ltd. | +86-86-18148706580 +8618826483838 | evan@tyvovo.com | China | 154 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6011 | 58 |
| Liaoning Pharmaceutical Innovation Co., Ltd | +8616588669988 | sales@pipharma.com.cn | China | 150 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 1142 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | hanson@sdhanjiang.com | China | 889 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 | sales06@tgybio.com | China | 938 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
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- May 22，2024
View Lastest Price from Diphenhydramine Hcl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-04-17 | diphenhydramine
58-73-1
|
US $50.00 / ASSAYS | 1ASSAYS | 99% | 100ton | Shanghai Yunao International Trade Co., Ltd | |
 |
2021-07-02 | Diphenhydramine Hcl
147-24-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- diphenhydramine
58-73-1
- US $50.00 / ASSAYS
- 99%
- Shanghai Yunao International Trade Co., Ltd
-
- Diphenhydramine Hcl
147-24-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd