Anisacril
- CAS No.
- 5129-14-6
- Chemical Name:
- Anisacril
- Synonyms
- Anisacril;α-(o-Anisyl)-β,β-diphenylacrylsaeure;2-(2-methoxyphenyl)-3,3-di(phenyl)acrylic acid;2-(2-methoxyphenyl)-3,3-di(phenyl)prop-2-enoic acid;Benzeneacetic acid, α-(diphenylmethylene)-2-methoxy-;2-(2-methoxyphenyl)-3,3-diphenylacrylic acid(WXG02282)
- CBNumber:
- CB01178036
- Molecular Formula:
- C22H18O3
- Molecular Weight:
- 330.38
- MDL Number:
- MOL File:
- 5129-14-6.mol
| FDA UNII | 5TB1FV429Z |
|---|
Anisacril Chemical Properties,Uses,Production
Originator
SCF 16046,Smith Kline
Manufacturing Process
A solution of Grignard reactive (prepared from 247 g of o-bromoanisole and
31.6 g of magnesium in 1500 ml of ether) is added dropwise to a solution of
91 g of diphenyl pyruvic acid in ether. The mixture is refluxed for 2 hours.
After cooling to the reaction mixture is added 5% hydrochloric acid and the
product is extracted with 5% solution of sodium hydroxide. α-(o-Anisyl)-β,β-
diphenyl lactic acid is precipitated by addition of concentrated hydrochloric
acid; yield 62 g, melting point 194-195°C.
4 g of α-(o-anisyl)-β,β-diphenyl lactic acid is heated at 210-215°C for 10-15
min. The α-(o-anisyl)-β,β-diphenyl acrylic acid is recrystallized from benzene,
yield 2.85 g (74%), melting point 195-196°C.
Therapeutic Function
Anorexic, Antihyperlipidemic
Anisacril Preparation Products And Raw materials
Anisacril Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lanospharma Laboratories Co.,Ltd | -- | sales@lanospharma.com | China | 6343 | 56 |
| Supplier | Advantage |
|---|---|
| Lanospharma Laboratories Co.,Ltd | 56 |