COLISTIN
- CAS No.
- 1066-17-7
- Chemical Name:
- COLISTIN
- Synonyms
- COLISTIN;kangdisu;totazina;colomycin;colimycin;Aids033059;coly-mycin;colymysins;kolimitsin;Aids-033059
- CBNumber:
- CB0169873
- Molecular Formula:
- C52H98N16O13
- Molecular Weight:
- 1155.43
- MDL Number:
- MFCD05662338
- MOL File:
- 1066-17-7.mol
| Boiling point | 807.67°C (rough estimate) |
|---|---|
| Density | 1.1050 (rough estimate) |
| refractive index | 1.6700 (estimate) |
| storage temp. | Store at -20°C |
| solubility | PBS (pH 7.2): 10 mg/ml |
| CAS DataBase Reference | 1066-17-7 |
| EWG's Food Scores | 1 |
| FDA UNII | Z67X93HJG1 |
| NCI Drug Dictionary | Coly-Mycin |
| ATC code | A07AA10,J01XB01 |
SAFETY
Risk and Safety Statements
| RIDADR | 3249 |
|---|---|
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | cat,LDLo,subcutaneous,250mg/kg (250mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: ATAXIABEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Antibiotiki. Vol. 5(4), Pg. 10, 1960. |
COLISTIN price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001999 | Colistin for system suitability European Pharmacopoeia (EP) Reference Standard | 1066-17-7 | y0001999 | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 23487 | Colistin ≥95% | 1066-17-7 | 100mg | $285 | 2021-12-16 | Buy |
| Cayman Chemical | 23487 | Colistin ≥95% | 1066-17-7 | 25mg | $89 | 2021-12-16 | Buy |
| AK Scientific | 9632AJ | Colistin | 1066-17-7 | 100mg | $484 | 2021-12-16 | Buy |
| AK Scientific | 9632AJ | Colistin | 1066-17-7 | 25mg | $220 | 2021-12-16 | Buy |
COLISTIN Chemical Properties,Uses,Production
Neurotoxicity and Nephrotoxicity
Colistin is an antibiotic which is being used more commonly now than when it was introduced because of its activity against multiresistant Gram-negative bacteria, especially Acinetobacter baumanii and Enterobacteriaceae producing extended spectrum β-lactamases. It had a bad reputation due to reports of neurotoxicity and nephrotoxicity. Recent studies have shown lower rates of nephrotoxicity than previously reported. However, in one of these reports, 7/42 patients with high serum creatinine values prior to colistin treatment developed renal failure.
Uses
Polymyxin E (colistin) is a complex of closely related cyclic peptides E1 and E2, with additional minor analogues. Polymyxin E is produced by Bacillus polymyxa var. colistinus, and is a highly basic, atypical cyclic peptide which incorporates the unusual amino acid, diaminobutyric acid. Head-to-tail coupling of lysine completes the macrocycle. Balancing the polar cyclic peptide is a hydrophobic tail with short chain fatty acids. Polymyxin E is a broad spectrum antibiotic active against Gram negative bacteria. The mechanism of action involves disruption of the bacterial outer membrane by a detergent-like effect.
brand name
Coly-Mycin (Monarch).
COLISTIN Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
| Hebei Qige Biological Technology Co. Ltd | +86 +8618733132031 | CHINA | 1313 | 58 | |
| AFINE CHEMICALS LIMITED | 0571-85134551 18958018566; | info@afinechem.com | China | 15377 | 58 |
View Lastest Price from COLISTIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-08 | amoxicillin
1066-17-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-04-12 | COLISTIN
1066-17-7
|
US $0.80 / kg | 1kg | 99.95%HTCL | 10Tons | Hebei Duling International Trade Co. LTD | |
 |
2021-01-19 | amoxicillin
1066-17-7
|
US $1.00 / PCS | 1KG | 99% | 10 mt | Hebei Guanlang Biotechnology Co., Ltd. |
-
- amoxicillin
1066-17-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- COLISTIN
1066-17-7
- US $0.80 / kg
- 99.95%HTCL
- Hebei Duling International Trade Co. LTD
-
- amoxicillin
1066-17-7
- US $1.00 / PCS
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
1066-17-7(COLISTIN)Related Search:
1of4