ChemicalBook >> CAS DataBase List >>2-AMINO-2-NORBORNANECARBOXYLIC ACID
2-AMINO-2-NORBORNANECARBOXYLIC ACID
- CAS No.
- 20448-79-7
- Chemical Name:
- 2-AMINO-2-NORBORNANECARBOXYLIC ACID
- Synonyms
- BCH;B-Bch;LAT1-IN-1;LAT1-IN-1 (BCH);2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-Aminonorbornane-2-carboxylic acid;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid;3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
- CBNumber:
- CB1384309
- Molecular Formula:
- C8H13NO2
- Molecular Weight:
- 155.19
- MDL Number:
- MFCD00167580
- MOL File:
- 20448-79-7.mol
Last updated:2023-06-30 15:45:59
| Melting point | >300 °C(lit.) |
|---|---|
| Boiling point | 295.5±23.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (Slightly) |
| form | Solid |
| pka | 2.58±0.20(Predicted) |
| color | White |
| Water Solubility | Soluble to 100 mM in water |
| CAS DataBase Reference | 20448-79-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
2-AMINO-2-NORBORNANECARBOXYLIC ACID price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A7902 | 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | 20448-79-7 | 100mg | $117 | 2024-03-01 | Buy |
| Sigma-Aldrich | A7902 | 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | 20448-79-7 | 1g | $662 | 2024-03-01 | Buy |
| Cayman Chemical | 15249 | BCH ≥98% | 20448-79-7 | 25mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 15249 | BCH ≥98% | 20448-79-7 | 50mg | $63 | 2024-03-01 | Buy |
| Sigma-Aldrich | A7902 | 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | 20448-79-7 | 250mg | $219 | 2024-03-01 | Buy |
2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells
Definition
ChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid.
General Description
2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.
Biochem/physiol Actions
2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells.
storage
Store at RT
2-AMINO-2-NORBORNANECARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-2-NORBORNANECARBOXYLIC ACID Suppliers
Global( 69)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19949 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
20448-79-7(2-AMINO-2-NORBORNANECARBOXYLIC ACID)Related Search:
3-AMINOPENTANE-3-CARBOXYLIC ACID
DL-ALPHA-METHYLLEUCINE
BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID
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1-AMINO-2-METHYLCYCLOHEXANECARBOXYLIC ACID
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1of4
2-AMINO-2-NORBORNANECARBOXYLIC ACID
2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID
BCH
2-AMINO-2-NORBORNANECARBOXYLIC ACID, 98% , MIXTURE OF ISOMERS
2-Amino-2-carboxy-bicyclo-2,2,1-heptane
2-Aminonorbornane-2-carboxylic acid
B-Bch
Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-amino-
2-AMino-2-norbornanecarboxylic acid aMino acid transport inhibitor
LAT1-IN-1 (BCH)
LAT1-IN-1
3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid
3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
LAT-1-IN-1,inhibit,LAT1 IN 1,LAT1IN1,Apoptosis,Inhibitor
20448-79-7
Biochemicals and Reagents
BioChemical
Amino Acids and Peptides
A - H
Modified Amino Acids
Peptide Synthesis
Others
Specialty Synthesis
Unnatural Amino Acid Derivatives