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Doxorubicin-SMCC

CAS No.
400647-59-8
Chemical Name:
Doxorubicin-SMCC
Synonyms
Doxorubicin-SMCC;N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin;5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
CBNumber:
CB14919822
Molecular Formula:
C39H42N2O14
Molecular Weight:
762.76
MDL Number:
MFCD32004617
MOL File:
400647-59-8.mol
Last updated:2023-05-15 08:29:04

Doxorubicin-SMCC Properties

Melting point 162-172 °C
Boiling point 1022.5±65.0 °C(Predicted)
Density 1.56±0.1 g/cm3(Predicted)
solubility Soluble in DMSO, DMF
pka 7.35±0.60(Predicted)

Doxorubicin-SMCC price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-24433 N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin 98% 400647-59-8 50mg $780 2021-12-16 Buy
BroadPharm BP-24433 N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin 98% 400647-59-8 100mg $1400 2021-12-16 Buy
BroadPharm BP-24433 N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin 98% 400647-59-8 250mg $2500 2021-12-16 Buy
Product number Packaging Price Buy
BP-24433 50mg $780 Buy
BP-24433 100mg $1400 Buy
BP-24433 250mg $2500 Buy

Doxorubicin-SMCC Chemical Properties,Uses,Production

Uses

Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

In vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Description

N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin is a maleimide attached Doxorubicin. It can conjugate with thiol containing molecules.

64987-85-5
25316-40-9
400647-59-8
Synthesis of Doxorubicin-SMCC from SMCC crosslinker and Doxorubicin hydrochloride

Doxorubicin-SMCC Preparation Products And Raw materials

Raw materials

Preparation Products

Doxorubicin-SMCC Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ChemExpress
+86-021-58950125 info@chemexpress.com China 555 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Abydos Scientific 025-84767922 18936879710 sales@abydoscientific.com China 1029 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 695 58
Nanchang Tianzhen Biotechnology Co., Ltd 13173652190 pomy@tanzhenbio.com China 1585 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85563444 18351873721 purchase@synzest.com China 10441 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
Doxorubicin-SMCC N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- 400647-59-8 C39H42N2O14 ADC LINKER