ChemicalBook >> CAS DataBase List >>4-(Bromomethyl)benzeneboronic acid pinacol ester
4-(Bromomethyl)benzeneboronic acid pinacol ester
- CAS No.
- 138500-85-3
- Chemical Name:
- 4-(Bromomethyl)benzeneboronic acid pinacol ester
- Synonyms
- 4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)benzyl BroMide;4-(Bromomethyl)phenylboronic acid pinacol;4-BROMOMETHYLPHENYLBORONIC ACID, PINACOL ESTER;4-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER;4-Bromomethylphenylboronic acid pinacol ester 95%;4-(BROMOMETHYL)BENZENEBORONICACIDPINACOLESTER,95%;tert-butyl 3-allyl-3-hydroxyazetidine-61-carboxylate;4-(bromomethyl)phenylboronic acid pinacol cyclic ester;4-(Bromomethyl)benzeneboronic acid pinacol cyclic ester;2-[(4-bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- CBNumber:
- CB1713271
- Molecular Formula:
- C13H18BBrO2
- Molecular Weight:
- 297
- MDL Number:
- MFCD02179493
- MOL File:
- 138500-85-3.mol
- MSDS File:
- SDS
Last updated:2024-05-14 11:12:52
| Melting point | 85-89 °C |
|---|---|
| Boiling point | 351.2±25.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Toluene |
| form | powder |
| color | white to off-white |
| BRN | 7921808 |
| InChI | InChI=1S/C13H18BBrO2/c1-12(2)13(3,4)17-14(16-12)11-7-5-10(9-15)6-8-11/h5-8H,9H2,1-4H3 |
| InChIKey | CBUOGMOTDGNEAW-UHFFFAOYSA-N |
| SMILES | O1C(C)(C)C(C)(C)OB1C1=CC=C(CBr)C=C1 |
| CAS DataBase Reference | 138500-85-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H314-H318-H315-H319 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 3261 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful/Irritant/Keep Cold | |||||||||
| TSCA | No | |||||||||
| HazardClass | IRRITANT | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
4-(Bromomethyl)benzeneboronic acid pinacol ester price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 718513 | 4-Bromomethylphenylboronic acid pinacol ester 95% | 138500-85-3 | 1g | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | 718513 | 4-Bromomethylphenylboronic acid pinacol ester 95% | 138500-85-3 | 5g | $200 | 2024-03-01 | Buy |
| TCI Chemical | T2945 | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Bromide >98.0%(GC)(T) | 138500-85-3 | 1g | $32 | 2024-03-01 | Buy |
| TCI Chemical | T2945 | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Bromide >98.0%(GC)(T) | 138500-85-3 | 5g | $89 | 2024-03-01 | Buy |
| Alfa Aesar | L19954 | 4-(Bromomethyl)benzeneboronic acid pinacol ester, 95% | 138500-85-3 | 1g | $108.65 | 2024-03-01 | Buy |
4-(Bromomethyl)benzeneboronic acid pinacol ester Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
2-[4-(Bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used in the synthesis of metalloproteinase-13 inhibitors in the treatment of osteoarthritis.
Synthesis
Pinacol p-tolueneborate (10.91g, 50.0mmol), bromosuccinimide (NBS, 9.91g, 55.0mmol), and azobisisobutyronitrile (AIBN, 0.44g, 2.0mmol) were dissolved in dry of carbon tetrachloride (CCl4, 200 mL), stirred at reflux for 14 hours. The mixture was filtered, the solvent was evaporated, and the mixture was dissolved in ethyl acetate (200 mL). Wash once with distilled water (100 mL) and saturated sodium chloride aqueous solution (100 mL), dry with anhydrous sodium sulfate, and rotary evaporate. Finally, use petroleum ether as the eluent for column chromatography separation to obtain 4-(Bromomethyl)benzeneboronic acid pinacol ester (11.30g, yield 76.1%).
Synthesis of 4-(Bromomethyl)benzeneboronic acid pinacol ester from N-Bromosuccinimide and 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)TOLUENE
4-(Bromomethyl)benzeneboronic acid pinacol ester Preparation Products And Raw materials
Raw materials
Preparation Products
Filgotinib
4-AMINOMETHYLPHENYLBORONIC ACID, PINACOL ESTER, HCL
4-(Cyanomethyl)benzeneboronic acid pinacol ester
3',6'-Bis{[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxy]-3H-[spiro(isobenzofuran-1,9,-xanthen]-3-one} FBBBE
N-Ethyl-N-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzyl)ethanaMine
Global( 279)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Creating Bio-pharm co., ltd. | +8613586099526 | post@creatingbiopharm.com | China | 217 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 19368 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15954 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9340 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
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| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
View Lastest Price from 4-(Bromomethyl)benzeneboronic acid pinacol ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-11 | 4-(Bromomethyl)benzeneboronic acid pinacol ester
138500-85-3
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2022-10-09 | 4-(Bromomethyl)benzeneboronic acid pinacol ester
138500-85-3
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-07-13 | 4-(Bromomethyl)benzeneboronic acid pinacol ester
138500-85-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 4-(Bromomethyl)benzeneboronic acid pinacol ester
138500-85-3
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 4-(Bromomethyl)benzeneboronic acid pinacol ester
138500-85-3
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 4-(Bromomethyl)benzeneboronic acid pinacol ester
138500-85-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
138500-85-3(4-(Bromomethyl)benzeneboronic acid pinacol ester)Related Search:
Potassium carbonate
Sodium Methoxide
4-Ethylphenylboronic acid
2-(4-Hexyl-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
4,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,1,3-benzothiadiazole
1of3
4-Bromomethylphenylboronic acid pinacol ester 95%
4-(BROMOMETHYL)BENZENEBORONIC ACID PINACOL ESTER
4-BROMOMETHYLPHENYLBORONIC ACID, PINACOL ESTER
4-(Bromomethyl)benzeneboronic acid pinacol cyclic ester
4-(Bromomethyl)phenylboronic acid pinacol cyclic ester~2-[(4-Bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
4-(Bromomethyl)phenylboronicacidpinacolcyclicester~2-[(4-Bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
2-[(4-bromomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
4-(bromomethyl)phenylboronic acid pinacol cyclic ester
4-BroMoMethylphenylboronic acid pinacol ester 2-(4-BroMoMethyl-phenyl)-4,4,5,5-tetraMethyl-[1,3,2]dioxaborolane 4-(BroMoMethyl)benzeneboronic acid pinacol ester
2-(4-(BroMoMe thyl)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolaMe
4-(Bromomethyl)phenylboronic acid pinacol
4-(BROMOMETHYL)BENZENEBORONICACIDPINACOLESTER,95%
1,3,2-Dioxaborolane, 2-[4-(bromomethyl)phenyl]-4,4,5,5-tetramethyl-
tert-butyl 3-allyl-3-hydroxyazetidine-61-carboxylate
4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)benzyl BroMide
138500-85-3
1358500-85-3
Boronic acids
blocks
BoronicAcids
Bromides