ChemicalBook >> CAS DataBase List >>Axitinib Impurity a
Axitinib Impurity a
- CAS No.
- 1347304-18-0
- Chemical Name:
- Axitinib Impurity a
- Synonyms
- Axitinib C;PF03482595);Axitinib M12;Axitinib Sulfoxide;Axitinib Impurity a;Axitinib metabolite M12;Axitinib sulfoxide (AG028458;N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfinyl]benzamide;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]benzamide;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-
- CBNumber:
- CB23038983
- Molecular Formula:
- C22H18N4O2S
- Molecular Weight:
- 402.47
- MDL Number:
- MFCD30747237
- MOL File:
- 1347304-18-0.mol
Last updated:2023-05-18 11:31:17
| Melting point | >225 (dec.) |
|---|---|
| Boiling point | 720.6±60.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 11.70±0.40(Predicted) |
| color | Light Yellow |
| FDA UNII | 55P8GY3IEK |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H361 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501 |
Axitinib Impurity a price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28042 | Axitinib Sulfoxide | 1347304-18-0 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 28042 | Axitinib Sulfoxide | 1347304-18-0 | 5mg | $211 | 2024-03-01 | Buy |
| TRC | A794885 | AxitinibSulfoxide | 1347304-18-0 | 10mg | $345 | 2021-12-16 | Buy |
| AK Scientific | 5029EA | Axitinibsulfoxide | 1347304-18-0 | 1mg | $166 | 2021-12-16 | Buy |
Axitinib Impurity a Chemical Properties,Uses,Production
Description
Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib . It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.
Uses
Axitinib Sulfoxide is a major metabolite of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
Axitinib Impurity a Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 59)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4505 | 50 | |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17994 | 56 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
1347304-18-0(Axitinib Impurity a)Related Search:
Axitinib Impurity a
Axitinib Sulfoxide
Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-
Axitinib C
Axitinib sulfoxide (AG028458
PF03482595)
Axitinib M12
N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]benzamide
N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfinyl]benzamide
Axitinib Impurity 5/Axitinib Sulfoxide/N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide
Axitinib metabolite M12
(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)sulfinyl)benzamide (Axitinib Impurity)
1347304-18-0