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ChemicalBook >> CAS DataBase List >> Axitinib Impurity a

Axitinib Impurity a

Axitinib Impurity a price.
  • $62 - $345
  • Product name: Axitinib Impurity a
  • CAS: 1347304-18-0
  • MF: C22H18N4O2S
  • MW: 402.47
  • EINECS:
  • MDL Number:MFCD30747237
  • Synonyms:Axitinib Impurity a;Axitinib Sulfoxide;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-;Axitinib C;Axitinib sulfoxide (AG028458;PF03482595);Axitinib M12;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]benzamide
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number5029EA
  • Product descriptionAxitinibsulfoxide
  • Packaging1mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28042
  • Product descriptionAxitinib Sulfoxide
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28042
  • Product descriptionAxitinib Sulfoxide
  • Packaging5mg
  • Price$211
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA794885
  • Product descriptionAxitinibSulfoxide
  • Packaging10mg
  • Price$345
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5029EA Axitinibsulfoxide 1mg $166 2021-12-16 Buy
Cayman Chemical 28042 Axitinib Sulfoxide 1mg $62 2024-03-01 Buy
Cayman Chemical 28042 Axitinib Sulfoxide 5mg $211 2024-03-01 Buy
TRC A794885 AxitinibSulfoxide 10mg $345 2021-12-16 Buy

Properties

Melting point :>225 (dec.)
Boiling point :720.6±60.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :11.70±0.40(Predicted)
color :Light Yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib . It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.

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