ChemicalBook >> CAS DataBase List >>(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione structure

CAS No.: 2088771-61-1

Chemical Name:: (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

Synonyms: Impurity FP-B;Sitagliptin-17;Sitagliptin Impurity 20;Sitagliptin FP Impurity B;Sitagliptin Impurity FP-B;Sitagliptin Triazecine Impurity;(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl);Sitagliptin FP Impurity B/ Sitagliptin Triazecine Analog;(R)-Sitagliptin Tablets EP Impurity FP-B ((R)-Sitagliptin Triazecine Analog);(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione

CBNumber:: CB23371367

Molecular Formula:: C16H13F6N5O2

Molecular Weight:: 421.3

MDL Number:: MFCD32669788

MOL File:: 2088771-61-1.mol

Last updated:2023-09-05 11:06:02

Request For Quotation

(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Properties

Melting point	>189°C (dec.)
Density	1.67±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
pka	12.02±0.40(Predicted)
form	Solid
color	White to Off-White
InChI	InChI=1S/C16H13F6N5O2/c17-9-6-11(19)10(18)4-7(9)3-8-5-12(28)23-1-2-27-13(14(29)24-8)25-26-15(27)16(20,21)22/h4,6,8H,1-3,5H2,(H,23,28)(H,24,29)/t8-/m1/s1
InChIKey	CJUCSNDPMOGZTM-MRVPVSSYSA-N
SMILES	N1[C@H](CC2=CC(F)=C(F)C=C2F)CC(=O)NCCN2C(C(F)(F)F)=NN=C2C1=O
FDA UNII	6EV5E35ZMR

(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Chemical Properties,Uses,Production

Uses

(10R)-Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes.

(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Suppliers

Global( 61)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9635	58
Hangzhou Huarong Pharm Co., Ltd.	571-86758373 +8613588754946	sales@huarongpharm.com	CHINA	3149	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	021-58123769 18678586262	info@paynepharm.com	China	1354	58
ShenZhen Davoos Tech Ltd	0752-5555973 13923768523	95372103@qq.com	China	670	58
Ji'nan tengbang pharmaceutical science and Technology Co., Ltd.	0531-88769236 15688889648	2685550793@qq.com	China	122	58

Supplier	Advantage
BOC Sciences	58
Standardpharm Co. Ltd.	58
Finetech Industry Limited	58
Hangzhou Huarong Pharm Co., Ltd.	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Shanghai Payne Pharmaceutical Technology Co.Ltd	58
ShenZhen Davoos Tech Ltd	58
Ji'nan tengbang pharmaceutical science and Technology Co., Ltd.	58

2088771-61-1((R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione)Related Search:

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate rac-Sitagliptin EP Impurity B HCl 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)-

Sitagliptin DeaMino IMpurity 1 Sitagliptin Impurity 1 Sitagliptin Impurity 26 Sitagliptin Impurity 14 Sitagliptin Impurity 28

Sitagliptin N-Phoshate IMpurity Sitagliptin Sitagliptin phosphate Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)- (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID Sitagliptin N-Boc IMpurity Sitagliptin Impurity 35

1of4

Impurity FP-B Sitagliptin Impurity 20 Sitagliptin-17 Sitagliptin FP Impurity B (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl) Sitagliptin impurity 6/Sitagliptin FP Impurity B/Sitagliptin Triazecine Analog/10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro [1,2,4] triazolo [3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione 1,2,4-Triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione, 6,7,10,11-tetrahydro-3-(trifluoromethyl)-10-[(2,4,5-trifluorophenyl)methyl]-, (10R)- (10R)?- 6,?7,?10,?11-?Tetrahydro-?3-?(trifluoromethyl)?-?10-?[(2,?4,?5-?trifluorophenyl)?methyl]?-1,?2,?4-?triazolo[3,?4-?c]?[1,?4,?7]?triazecine-?8,?12(5H,?9H)?-?dione Sitagliptin FP Impurity B/ Sitagliptin Triazecine Analog (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione Sitagliptin Impurity FP-B (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione? (Sitagliptin Impurity） Sitagliptin Triazecine Impurity (R)-Sitagliptin Tablets EP Impurity FP-B ((R)-Sitagliptin Triazecine Analog) 2088771-61-1 C16H13F6N5O2