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PROSTAGLANDIN D2

PROSTAGLANDIN D2 Structure
PROSTAGLANDIN D2 structure
CAS No.
41598-07-6
Chemical Name:
PROSTAGLANDIN D2
Synonyms
PGDS;PGD2;Prostaglandin D?;PROSTAGLANDIN D2;PROSTAGLANDINS D2;PGD2 (Prostaglandin D2);RP23-47P18.11-006, 21kDa;11-dehydroprostaglandinf2-alpha;Prostaglandin D2 MaxSpecStandard;prostaglandin D2 synthase (brain)
CBNumber:
CB2433095
Molecular Formula:
C20H32O5
Molecular Weight:
352.47
MDL Number:
MFCD00077857
MOL File:
41598-07-6.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:10
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PROSTAGLANDIN D2 Properties

Melting point 68°C
Boiling point 406.07°C (rough estimate)
alpha +7.5°(D/21℃)(c=1,THF)
Density 1.0601 (rough estimate)
refractive index 1.6120 (estimate)
storage temp. -20°C
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly), THF (Slightly)
pka 4.76±0.10(Predicted)
form White solid
color White to Light Orange
BRN 2170623
Stability Light Sensitive
FDA UNII RXY07S6CZ2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H360
Precautionary statements  P201-P301+P312+P330-P308+P313
Hazard Codes  T
Risk Statements  60-22
Safety Statements  53-22-26-36
WGK Germany  3
RTECS  UK7930000
F  10
NFPA 704
0
2 0

PROSTAGLANDIN D2 price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P5172 Prostaglandin D2 ≥95%, synthetic 41598-07-6 1mg $200 2024-03-01 Buy
Sigma-Aldrich SAB2502046 Anti-Ptgds antibody produced in goat affinity isolated antibody, buffered aqueous solution 41598-07-6 100μG $568 2024-03-01 Buy
Sigma-Aldrich 538909 Prostaglandin D? 41598-07-6 1mg $182 2024-03-01 Buy
Cayman Chemical 12010 Prostaglandin D2 ≥98% 41598-07-6 1mg $49 2024-03-01 Buy
Cayman Chemical 12010 Prostaglandin D2 ≥98% 41598-07-6 5mg $216 2024-03-01 Buy
Product number Packaging Price Buy
P5172 1mg $200 Buy
SAB2502046 100μG $568 Buy
538909 1mg $182 Buy
12010 1mg $49 Buy
12010 5mg $216 Buy

PROSTAGLANDIN D2 Chemical Properties,Uses,Production

Description

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as β-trace. In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 μM.

Uses

Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma.

Definition

ChEBI: A member of the class of prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- s ereoisomer).

Biochem/physiol Actions

Primary prostaglandin in brain; induces inflammation; stimulates adenylyl cyclase.

PROSTAGLANDIN D2 synthesis

61305-35-9
41598-07-6
Synthesis of PROSTAGLANDIN D2 from (4R)-(+)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE

PROSTAGLANDIN D2 Preparation Products And Raw materials

Raw materials

Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-oxo-, (5Z,9α,13E,15S)- (9CI) Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-hydroxy-, (5Z,9α,11α,13E,15S)- (9CI) Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-hydroxy-, methyl ester, (5Z,9α,11α,13E,15S)- (9CI) Prosta-5,13-dien-1-oic acid, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-11-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (5Z,9α,11α,13E,15S)- (9CI) Prosta-5,13-dien-1-oic acid, 15-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-9-hydroxy-11-[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester, (5Z,9α,11α,13E,15S)- (9CI)
5-Heptynoic acid, 7-oxo-, methyl ester 2H-Pyran, tetrahydro-2-[[(1S)-1-[(1E)-2-iodoethenyl]hexyl]oxy]- (4R)-(+)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE

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Preparation Products

PROSTAGLANDIN D2 Suppliers

Global( 69)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Syntechem Co.,Ltd info@syntechem.com China 12990 57
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3423 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 18112977050 cb6@aikonchem.com China 16687 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Aladdin Scientific 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky（shanghai）International Co.,Ltd. 50
Syntechem Co.,Ltd 57
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Sigma-Aldrich 80

41598-07-6(PROSTAGLANDIN D2)Related Search:

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PROSTAGLANDIN G2 PROSTAGLANDIN H1 Latanoprost acid ENPROSTIL PROSTAGLANDIN J2
PROSTAGLANDIN B2 Inositol Prostaglandin E2 PROSTAGLANDIN A2 PROSTAGLANDIN A1
Latanoprost Lactone Diol Carboprost Acid Red 94

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9,15-dihydroxy-11-oxo-,(5z,9-alpha,13e,15s)-prosta-13-dien-1-oicacid prostaglandin D2 cell culture tested prostaglandind2synthetichygroscopic (5z,9α,13e,15s)-9,15-dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid 7-[(1R,2R,5S)-5-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid PGD2, (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid (5Z,13E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic acid Prostaglandin D2,(5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid, PGD2 Prostaglandin D2 Lipid Maps MS Standard (Z)-7-((1R,2R,5S)-5-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-3-oxocyclopentyl)hept-5-enoic acid Anti-Ptgds antibody produced in goat PGDS prostaglandin D2 synthase (brain) RP23-47P18.11-006, 21kDa PGD2 (Prostaglandin D2) Prostaglandin D? PROSTAGLANDIN D2 PROSTAGLANDINS D2 PGD2 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID [5Z,9ALPHA,13E,15S]9,15-DIHYDROXY-11-OXOPROSTA-5,13-DIEN-1-OIC ACID 11-dehydroprostaglandinf2-alpha Prostaglandin D2 MaxSpecStandard Prostaglandin D - CAS 41598-07-6 - Calbiochem Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S)- 41598-07-6 Fatty Acids Prostaglandins Lipids BioChemical Biochemicals and Reagents