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ChemicalBook >> CAS DataBase List >>1,2,3,4,5,6-HEXABROMOCYCLOHEXANE

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Structure
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE structure
CAS No.
1837-91-8
Chemical Name:
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE
Synonyms
NSC 7908;JAK2 INHIBITOR II;BENZENE HEXABROMIDE;6-Hexabromocyclohexane;trans-α-Benzene hexabromide;1,2,3,4,5,6-Hexabromcyclohexan;1,2,3,4,5,6-HEXABROMOCYCLOHEXANE;1,2,3,4,5,6-hexabromo-cyclohexan;Cyclohexane, 1,2,3,4,5,6-hexabromo-;JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem
CBNumber:
CB3337703
Molecular Formula:
C6H6Br6
Molecular Weight:
557.54
MDL Number:
MFCD00059127
MOL File:
1837-91-8.mol
Last updated:2023-12-28 18:13:10
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1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Properties

Melting point 218.0 to 223.0 °C
storage temp. Store at RT
solubility DMSO: soluble2mg/mL (clear solution, warmed)
form powder
color white to beige
CAS DataBase Reference 1837-91-8(CAS DataBase Reference)
EPA Substance Registry System Cyclohexane, 1,2,3,4,5,6-hexabromo- (1837-91-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn
Risk Statements  36/37/38-36-22
Safety Statements  26-36/37/39
WGK Germany  3
TSCA  Yes

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 420132 JAK2 Inhibitor II 1837-91-8 25mg $172 2024-03-01 Buy
Sigma-Aldrich SML0455 1,2,3,4,5,6-Hexabromocyclohexane ≥98% (HPLC) 1837-91-8 50mg $127 2022-05-15 Buy
TCI Chemical H0368 1,2,3,4,5,6-Hexabromocyclohexane 1837-91-8 5g $326 2021-12-16 Buy
TCI Chemical H0368 1,2,3,4,5,6-Hexabromocyclohexane min. 97.0 % 1837-91-8 1G $109 2021-12-16 Buy
Alfa Aesar J60853 1,2,3,4,5,6-Hexabromocyclohexane 1837-91-8 1g $99.65 2024-03-01 Buy
Product number Packaging Price Buy
420132 25mg $172 Buy
SML0455 50mg $127 Buy
H0368 5g $326 Buy
H0368 1G $109 Buy
J60853 1g $99.65 Buy

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Chemical Properties,Uses,Production

Uses

1,2,3,4,5,6-Hexabromocyclohexane is a potent and specific inhibitor of JAK2 autophosphorylation.

Definition

ChEBI: 1,2,3,4,5,6-hexabromocyclohexane is a bromohydrocarbon that is cyclohexane in which the hydrogen at positions 1,2,3,4,5 and 6 have been replaced by bromo groups. It is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a bromohydrocarbon and a bromoalkane. It derives from a hydride of a cyclohexane.

Biological Activity

Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μ M of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μ M elimates nearly all JAK2 activity. Non-cytotoxic at 100 μ M.

storage

Room temperature

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Preparation Products And Raw materials

Raw materials

Preparation Products

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 18226 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Alfa Chemistry 		+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32360 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109 market03@meryer.com China 40240 62
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24539 81
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
TargetMol Chemicals Inc. 		58
Alfa Chemistry 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Mainchem Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
TCI (Shanghai) Development Co., Ltd. 81

View Lastest Price from 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE pictures 2023-12-29 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE
1837-91-8
 US $101.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Spectrum

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE(1837-91-8)MS1,2,3,4,5,6-HEXABROMOCYCLOHEXANE(1837-91-8)IR11,2,3,4,5,6-HEXABROMOCYCLOHEXANE(1837-91-8)IR21,2,3,4,5,6-HEXABROMOCYCLOHEXANE(1837-91-8)Raman

1837-91-8(1,2,3,4,5,6-HEXABROMOCYCLOHEXANE)Related Search:

1,2,5,6-TETRABROMOHEXANE 1,5-Dibromopentane 3,4-DIBROMOHEXANE 1,2,3,4-Tetrabromobutane 2,4-DIBROMOPENTANE
1,2,4-Tribromobutane 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE 1,3-Dibromobutane 2,5-Dibromohexane TRANS-1,2-DIBROMOCYCLOHEXANE
1,2-DIBROMOCYCLOHEXANE 1,2-Dibromobutane 1,4-Dibromopentane 2,3-DIBROMOBUTANE Bromocyclohexane
1,4-Dibromobutane 1,2,3-Tribromopropane 1,2-Dibromopentane

1of4

1,2,3,4,5,6-hexabromo-cyclohexan 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE BENZENE HEXABROMIDE JAK2 INHIBITOR II trans-α-Benzene hexabromide 1,2,3,4,5,6-Hexabromcyclohexan NSC 7908 JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem Cyclohexane, 1,2,3,4,5,6-hexabromo- 6-Hexabromocyclohexane 1,2,3,4,5,6Hexabromocyclohexane,1,2,3,4,5,6 Hexabromocyclohexane 1837-91-8 C6H6Br6