ChemicalBook >> CAS DataBase List >>TRAM-34
TRAM-34
- CAS No.
- 289905-88-0
- Chemical Name:
- TRAM-34
- Synonyms
- RAM-34;CS-1574;TRAM34;TRAM 34;TRAM-34 USP/EP/BP;Triarylmethane-34;Clotrimazole Impurity 8;Des Imidazole 1-pyrazole;Clotrimazole TRAM-34 Impurity;TRAM34;TRAM 34;TRIARYLMETHANE-34;1-[(2-Chlorophenyl)diphenylmethyl]-
- CBNumber:
- CB3505056
- Molecular Formula:
- C22H17ClN2
- Molecular Weight:
- 344.84
- MDL Number:
- MFCD09842562
- MOL File:
- 289905-88-0.mol
- MSDS File:
- SDS
Last updated:2023-09-04 16:42:00
| Melting point | 145-147°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: ~11 mg/mL |
| form | solid |
| color | off-white |
| Water Solubility | Soluble in DMSO at 2mg/ml. Insoluble in water |
| CAS DataBase Reference | 289905-88-0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H413 | |||||||||
| Precautionary statements | P273-P301+P312+P330 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
TRAM-34 price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T6700 | TRAM 34 ≥98% (HPLC), solid | 289905-88-0 | 5mg | $194 | 2024-03-01 | Buy |
| Sigma-Aldrich | T6700 | TRAM 34 ≥98% (HPLC), solid | 289905-88-0 | 25mg | $610 | 2024-03-01 | Buy |
| Alfa Aesar | J60019 | TRAM 34 | 289905-88-0 | 25mg | $286 | 2023-06-20 | Buy |
| Cayman Chemical | 23385 | TRAM 34 ≥98% | 289905-88-0 | 5mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 23385 | TRAM 34 ≥98% | 289905-88-0 | 10mg | $68 | 2024-03-01 | Buy |
TRAM-34 Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Definition
ChEBI: TRAM-34 is an organochlorine compound.
Biological Activity
Highly selective blocker of intermediate conductance Ca 2+ -activated K + channels (IK Ca 1, K Ca 3.1) (K d = 20 nM). Exhibits 200-1500-fold selectivity over K V , BK Ca , SK Ca , Na + , CRAC and Cl - channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.
Biochem/physiol Actions
TRAM-34 exhibits 100-fold selectivity (Kd = 20 nM) for IKCa1 channels over other K+ channels (Charybdotoxin, Kd = 5 nM, Clotrimazole, Kd = 70 nM; Nitrendipine Kd = 900 nM). Furthermore, TRAM-34 is known to suppress the activation of human T lymphocytes,.
storage
+4°C
TRAM-34 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 130)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27644 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
Triarylmethane-34
CS-1574
TRAM34;TRAM 34
1-[(2-chlorophenyl)-diphenylmethyl]pyrazole
Clotrimazole TRAM-34 Impurity
Clotrimazole Impurity 8
TRAM34;TRAM 34;TRIARYLMETHANE-34
1-[(2-Chlorophenyl)diphenylmethyl]-
1H-Pyrazole, 1-[(2-chlorophenyl)diphenylmethyl]-
TRAM-34 USP/EP/BP
4-chloro-2,3-dihydro-1H-indene-6-carboxylicacid
Carbonochloridicacid,9-methylphenylester
RAM-34
TRAM34,Inhibitor,Potassium Channel,KcsA,inhibit,TRAM-34
Des Imidazole 1-pyrazole
289905-88-0
Heterocyclic Compounds
Heterocycles
Inhibitors