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12(S)-HPETE

CAS No.
71774-10-2
Chemical Name:
12(S)-HPETE
Synonyms
12(S)-HPETE;12(S)HpETE,12(S) HpETE;ZIOZYRSDNLNNNJ-LQWMCKPYSA-N;12(S)-HpETE Lipid Maps MS Standard;12(S)-Hydroperoxy-eicosatetraenoic acid;(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid;12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID;12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid
CBNumber:
CB4154161
Molecular Formula:
C20H32O4
Molecular Weight:
336.47
MDL Number:
MFCD00063585
MOL File:
71774-10-2.mol
Last updated:2023-06-08 09:03:09

12(S)-HPETE Properties

Boiling point 518.0±50.0 °C(Predicted)
Density 1.013±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form Liquid.
pka 4.75±0.10(Predicted)
FDA UNII 54G1W9LPV0

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

12(S)-HPETE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 71774-10-2 25μg $131 2024-03-01 Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 71774-10-2 50μg $246 2024-03-01 Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 71774-10-2 100μg $466 2024-03-01 Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 71774-10-2 250μg $1030 2024-03-01 Buy
TRC H456410 12(S)-HPETE 71774-10-2 50μg $225 2021-12-16 Buy
Product number Packaging Price Buy
44570 25μg $131 Buy
44570 50μg $246 Buy
44570 100μg $466 Buy
44570 250μg $1030 Buy
H456410 50μg $225 Buy

12(S)-HPETE Chemical Properties,Uses,Production

Description

12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE. Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids. 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.

Uses

12(S)-HPETE is a fatty acid and an activator of human blood leukocyte 5-LO.

Definition

ChEBI: 12(S)-HPETE is the (S)-enantiomer of 12-HPETE. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,10,14-tetraenoic acid. It is a conjugate acid of a 12(S)-HPETE(1-). It is an enantiomer of a 12(R)-HPETE.

12(S)-HPETE Preparation Products And Raw materials

Raw materials

Preparation Products

12(S)-HPETE Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1977 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3004 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
SHANGHAI ZZBIO CO., LTD. 021-58979353 18019707223 tech@zzbioco.com China 12096 58
12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID 12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID 12(S)-HPETE (12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid (5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid (5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid 12(S)-Hydroperoxy-eicosatetraenoic acid (5Z,8Z,10Z,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid 12(S)-HpETE Lipid Maps MS Standard ZIOZYRSDNLNNNJ-LQWMCKPYSA-N 12(S)HpETE,12(S) HpETE 5,8,10,14-Eicosatetraenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,12S,14Z)- 71774-10-2