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Piclamilast

CAS No.
144035-83-6
Chemical Name:
Piclamilast
Synonyms
RP 73401;RPR 73401;piclamilas;Piclamilast;N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide;3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide;Benzamide,3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-;inhibit,Phosphodiesterase (PDE),RPR73401,AML,phosphodiesterase,PDE,RAR,RP-73401,Inhibitor,Piclamilast,RP73401,RPR-73401,ATRA,cAMP
CBNumber:
CB51328847
Molecular Formula:
C18H18Cl2N2O3
Molecular Weight:
381.25
MDL Number:
MOL File:
144035-83-6.mol
Last updated:2023-06-30 15:45:59

Piclamilast Properties

Boiling point 447.8±45.0 °C(Predicted)
Density 1.370
storage temp. 2-8°C
solubility DMSO: soluble20mg/mL, clear
pka 10.10±0.70(Predicted)
form powder
color white to beige
FDA UNII WM58D7C3ZT

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

Piclamilast price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0585 Piclamilast ≥98% (HPLC) 144035-83-6 5mg $128 2024-03-01 Buy
Sigma-Aldrich SML0585 Piclamilast ≥98% (HPLC) 144035-83-6 25mg $496 2024-03-01 Buy
Cayman Chemical 29170 Piclamilast 144035-83-6 1mg $39 2024-03-01 Buy
Cayman Chemical 29170 Piclamilast 144035-83-6 5mg $127 2024-03-01 Buy
Cayman Chemical 29170 Piclamilast 144035-83-6 10mg $233 2024-03-01 Buy
Product number Packaging Price Buy
SML0585 5mg $128 Buy
SML0585 25mg $496 Buy
29170 1mg $39 Buy
29170 5mg $127 Buy
29170 10mg $233 Buy

Piclamilast Chemical Properties,Uses,Production

Uses

Piclamilast is a potent and selective phosphodiesterase-4 (PDE4) inhibitor. Piclamilast may offer therapeutic strategies in respiratory diseases, including asthma and chronic obstructive pulmonary disease. Piclamilast may also provide a treatment option for pre-term infants with bronchopulmonary dysplasia (BPD).

Definition

ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-(cyclopentyloxy)-4-methoxybenzoic acid with the primary amino group of 3,5-dichloropyridin-4-amine.

storage

Store at RT

Piclamilast Preparation Products And Raw materials

Raw materials

Preparation Products

Piclamilast Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
ZHIWE CHEMTECH CO LTD 021-20221225 13917446399 sales@zhiwe.net China 579 61
Shanghai Hekang Biotechnology Co., Ltd. 18939837085 youchemicals@gmail.com China 1823 55
AN PharmaTech Co Ltd 86(21)68097365 sales@anpharma.net China 4901 55
Shanghai Boyners Pharm-Tech Co., Ltd. 021-54581719 13817873692 mkt@boynerspharm.com China 1725 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Benzamide,3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy- RP 73401 RPR 73401 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-4-methoxybenzamide 3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide Piclamilast 3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide piclamilas inhibit,Phosphodiesterase (PDE),RPR73401,AML,phosphodiesterase,PDE,RAR,RP-73401,Inhibitor,Piclamilast,RP73401,RPR-73401,ATRA,cAMP 144035-83-6 Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals