ChemicalBook >> CAS DataBase List >>SYROSINGOPINE

SYROSINGOPINE

CAS No.
84-36-6
Chemical Name:
SYROSINGOPINE
Synonyms
HF-41T;Ipores;su3118;Isotens;Su 3118;Raunova;arbonate;Etropres;Isotense;Londomin
CBNumber:
CB5193628
Molecular Formula:
C35H42N2O11
Molecular Weight:
666.72
MDL Number:
MFCD00017411
MOL File:
84-36-6.mol
Last updated:2023-05-25 18:01:11

SYROSINGOPINE Properties

Melting point 175°C
Boiling point 686.09°C (rough estimate)
Density 1.2536 (rough estimate)
refractive index 1.5300 (estimate)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 18.11±0.70(Predicted)
form Solid
color Beige
LogP 3.510 (est)
CAS DataBase Reference 84-36-6(CAS DataBase Reference)
FDA UNII PPG46JF0EG

SAFETY

Risk and Safety Statements

RIDADR  1544
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 oral in rat: > 2gm/kg

SYROSINGOPINE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FS65931 Syrosingopine 84-36-6 25mg $100 2021-12-16 Buy
Biosynth Carbosynth FS65931 Syrosingopine 84-36-6 50mg $175 2021-12-16 Buy
Biosynth Carbosynth FS65931 Syrosingopine 84-36-6 100mg $300 2021-12-16 Buy
Biosynth Carbosynth FS65931 Syrosingopine 84-36-6 250mg $625 2021-12-16 Buy
American Custom Chemicals Corporation API0004304 SYROSINGOPINE 95.00% 84-36-6 10MG $782.23 2021-12-16 Buy
Product number Packaging Price Buy
FS65931 25mg $100 Buy
FS65931 50mg $175 Buy
FS65931 100mg $300 Buy
FS65931 250mg $625 Buy
API0004304 10MG $782.23 Buy

SYROSINGOPINE Chemical Properties,Uses,Production

Chemical Properties

White or slightly yellowish powder. Practically insoluble in water; slightly soluble in methanol; soluble in chloroform and acetic acid.

Originator

Singoserp,Ciba,US,1958

Uses

Medicine.

Uses

Syrosingopine (CAS# 84-36-6) is a pharmaceutical used to treat hypertension.

Definition

Methyl reserpate ester of syringic acid ethyl carbonate. An analog of reserpine.

Manufacturing Process

1 part by weight of methyl reserpate and 1.9 parts by weight of Ocarbethoxysyringoyl chloride were dissolved in 20 parts by volume of anhydrous pyridine and allowed to stand at 5°C for 3 days. An equal volume of ice was then added, and the mixture evaporated to dryness in vacuo. The residue was dissolved in 50 parts by volume of chloroform and washed in succession with three 50 parts by volume portions of 2% sodium hydroxide solution and two 50 parts by volume portions of water. The chloroform solution was dried over sodium sulfate and evaporated to dryness. The residue was dissolved in 15 parts by volume of benzene and chromatographed on a 10 part by weight column of II-III grade alumina. Eluates of benzene, 90 benzene: 10 acetone, 80 benzene: 20 acetone, 60 benzene: 40 acetone; and acetone were removed. From the 90 benzene: 10 acetone eluate there was recovered crystalline methyl O-(O'-carbethoxysyringoyl)-reserpate, melting point 175°C to 178°C, on crystallization from acetone.

Therapeutic Function

Antihypertensive

target

HCV | Antifection | Androgen Receptor | Histone Methyltransferase | NF-kB | Mdm2

SYROSINGOPINE Preparation Products And Raw materials

Raw materials

Preparation Products

SYROSINGOPINE Suppliers

Global( 101)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 2263 58
Aktin Chemicals, Inc.
028-85159085 info@aktinchem.com CHINA 1025 58
AFINE CHEMICALS LIMITED
0571-85134551 18958018566; info@afinechem.com China 15377 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9635 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923 1026@dideu.com China 9020 58

View Lastest Price from SYROSINGOPINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Syrosingopine  pictures 2020-02-26 Syrosingopine
84-36-6
US $0.00-0.00 / Kg 1KG 99.0%+ 1000 tons Shaanxi Dideu Medichem Co. Ltd
SYROSINGOPINE pictures 2020-02-21 SYROSINGOPINE
84-36-6
US $8.00 / KG 1g >98% HPLC kg--ton Career Henan Chemical Co
  • Syrosingopine  pictures
  • Syrosingopine
    84-36-6
  • US $0.00-0.00 / Kg
  • 99.0%+
  • Shaanxi Dideu Medichem Co. Ltd
  • SYROSINGOPINE pictures
  • SYROSINGOPINE
    84-36-6
  • US $8.00 / KG
  • >98% HPLC
  • Career Henan Chemical Co
SYROSINGOPINE(RG) 3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) (8CI) NSC 77030 Reserpic acid, methyl ester, ester with syringic acid, ethyl carbonate (6CI) Yohimban-16-carboxylic acid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-, methyl ester, (3b,16b,17a,18b,20a)- (9CI) Isotens SYROSINGOPINE 18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-yohimban-16-carboxylic acid methyl ester 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate arbonate Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ethyl carbonate, ester with methyl reserpate benzoicacid,4-hydroxy-3,5-dimethoxy-,ethylcarbonate,esterwithmethylre Carbethoxysyringoyl methylreserpate carbethoxysyringoylmethylreserpate Elufinesin Etropres HF-41T imethoxy-,methylester,esterwith4-hydroxy-3,5-dimethoxybenzoicacidethylc Ipores Siringina Siringone Siriserpin Siroshuten Su 3118 su3118 Syringic acid ethyl carbonate ester with methyl reserpate syringicacidethylcarbonateesterwithmethylreserpate Syringopine Syrosingopin thylcarbonate Vegaserpina Yohimban-16-carboxylic acid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha Isotense Londomin Menatensina Methyl 18-((4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxyyohimban-16-carboxylate Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate 4-hydroxy Methyl carbethoxysyringoyl reserpate Methyl reserpate ester of syringic acid ethyl carbonate Methyl reserpate, 4-ethoxycarbonyl-3,5-dimethoxybenzoic acid ester methylcarbethoxysyringoylreserpate methylreserpate,4-ethoxycarbonyl-3,5-dimethoxybenzoicacidester methylreserpateesterofsyringicacidethylcarbonate Neoreserpan Nichiserpine-S Novoserpina Raunova Reserpic acid, methyl ester, ester with 4-hydroxy-3,5-dimethoxybenzoic acid ethyl carbonate reserpicacid,methylester,esterwith4-hydroxy-3,5-dimethoxybenzoicacide Revelox-Wirkstoff Seniramin Seringina Serpagon Singoserp Siringal (1S,2R,3R,4aS,13bR,14aS)-3-(4-carbethoxyoxy-3,5-dimethoxy-benzoyl)oxy-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]$b-carboline-1-carboxylic acid methyl ester Reserpine Impurity 10