Phytosphingosine
- CAS No.
- 554-62-1
- Chemical Name:
- Phytosphingosine
- Synonyms
- 4-HYDROXYSPHINGANINE;D-ribo-Phytosphingosine;(2S,3S,4R)-2-aminooctadecane-1,3,4-triol;Salicyl phytosphingosine;Glycolipid;Phytospingosine;4-D-Hydroxysphinganine;hytosphingosine;Phytosphingosine>C18-Phytosphingosine
- CBNumber:
- CB5289606
- Molecular Formula:
- C18H39NO3
- Molecular Weight:
- 317.51
- MDL Number:
- MFCD02259274
- MOL File:
- 554-62-1.mol
- MSDS File:
- SDS
| Melting point | 102 °C |
|---|---|
| Boiling point | 483.7±40.0 °C(Predicted) |
| Density | 0.983 |
| vapor pressure | 0.2Pa at 20℃ |
| refractive index | 9 ° (C=1, Pyridine) |
| storage temp. | −20°C |
| solubility | Soluble in Ethanol (up to 2 mg/ml). |
| pka | 11.91±0.45(Predicted) |
| form | White to off-white solid. |
| color | White |
| Water Solubility | 2.6mg/L at 20℃ |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month. |
| InChI | InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1 |
| InChIKey | AERBNCYCJBRYDG-KSZLIROESA-N |
| SMILES | C(O)[C@H](N)[C@H](O)[C@H](O)CCCCCCCCCCCCCC |
| LogP | 6.2 at 22℃ |
| EWG's Food Scores | 1 |
| FDA UNII | GIN46U9Q2Q |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| WGK Germany | 1 | |||||||||
| HS Code | 29221990 | |||||||||
| NFPA 704 |
|
Phytosphingosine price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P2795 | Phytosphingosine hydrochloride ≥98%, from | 554-62-1 | 5mg | $393 | 2024-03-01 | Buy |
| TCI Chemical | P1765 | Phytosphingosine >98.0%(T) | 554-62-1 | 1g | $92 | 2024-03-01 | Buy |
| TCI Chemical | P1765 | Phytosphingosine >98.0%(T) | 554-62-1 | 5g | $276 | 2024-03-01 | Buy |
| Cayman Chemical | 20217 | Phytosphingosine ≥95% | 554-62-1 | 5mg | $39 | 2024-03-01 | Buy |
| Cayman Chemical | 20217 | Phytosphingosine ≥95% | 554-62-1 | 10mg | $70 | 2024-03-01 | Buy |
Phytosphingosine Chemical Properties,Uses,Production
Description
Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330]
Chemical Properties
Off-White Solid
Uses
Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation.
Uses
phytosphingosine is a sphingolipid that can improve the overall condition of skin and hair. Some sources site anti-microbial and anti-inflammatory properties. Research indicates similar activity to retinoic acid, in which case it may be particularly beneficial for aging and photo-aging skin.
Definition
ChEBI: Phytosphingosine is a sphingoid, an amino alcohol and a triol. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a N-acyl-beta-D-galactosylphytosphingosine and a sphinganine. It is a conjugate base of a phytosphingosine(1+).
Origin
In 1884, chemist J.L.W coined the word phytosphingosine, which was taken from the term “sphingoid”, a major component in all biological membranes. There are four types of sphingoid bases and phytosphingosine is one of them. Phytosphingosine is a widely distributed natural sphingoid base and found in fungi, plants, and animals.
Flammability and Explosibility
Not classified
Veterinary Drugs and Treatments
Phytosphingosine is a unique topical antiseborrheic compound. It is in a class called ceramides which are waxy materials meant to meant to mimic the normal lipid composition of the stratum corneum. It may also have some antiinflammatory and antimicrobial properties.
References
1) Fischer et al. (2012), Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria; Antimicrob. Agents Chemother., 56 1157 2) Fischer et al. (2013), Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage; Skin Pharmacol. Physiol., 26 36
Phytosphingosine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 | sales@zhswyy.com | China | 242 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 1685 | 58 |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 781 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Related articles
- Benefits Of Phytosphingosine For Skin
- Phytosphingosine (PHS) is a sphingoid critical component of phytoceramides NP, AP, and EOP. PHS has been known to have anti-in....
- Dec 26，2023
View Lastest Price from Phytosphingosine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-11 | PHYTOSPHINGOSINE
554-62-1
|
US $0.00-0.00 / kg | 0.10000000149011612kg | 98% HPLC | 20000kgs | Chongqing Zhihe Biopharmaceutical Co., Ltd. | |
 |
2024-05-11 | Ceramides Phytosphingosine transparent oil mixture
554-62-1
|
US $0.00-0.00 / kg | 0.10000000149011612kg | 98% HPLC | 20000kgs | Chongqing Zhihe Biopharmaceutical Co., Ltd. | |
 |
2024-05-11 | Phytosphingosine
554-62-1
|
US $0.00-0.00 / kg | 0.10000000kg | 99% | 20tons | Chongqing Zhihe Biopharmaceutical Co., Ltd. |
-
- PHYTOSPHINGOSINE
554-62-1
- US $0.00-0.00 / kg
- 98% HPLC
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
-
- Ceramides Phytosphingosine transparent oil mixture
554-62-1
- US $0.00-0.00 / kg
- 98% HPLC
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
-
- Phytosphingosine
554-62-1
- US $0.00-0.00 / kg
- 99%
- Chongqing Zhihe Biopharmaceutical Co., Ltd.