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JACOLINE

CAS No.
480-76-2
Chemical Name:
JACOLINE
Synonyms
Jacolin;JACOLINE;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
CBNumber:
CB61438381
Molecular Formula:
C18H27NO7
Molecular Weight:
369.41
MDL Number:
MFCD00871325
MOL File:
480-76-2.mol
Last updated:2023-07-12 17:04:18

JACOLINE Properties

Melting point 221°C
Boiling point 583.5±50.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 12.40±0.60(Predicted)
FDA UNII USC51AR5V5

JACOLINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC J210403 Jacoline 480-76-2 2.5mg $2640 2021-12-16 Buy
Biosynth Carbosynth XJ161762 Jacoline 480-76-2 1mg $250 2021-12-16 Buy
Biosynth Carbosynth XJ161762 Jacoline 480-76-2 2mg $400 2021-12-16 Buy
American Custom Chemicals Corporation PXT0001950 JACOLINE 95.00% 480-76-2 5MG $505.59 2021-12-16 Buy
Biosynth Carbosynth XJ161762 Jacoline 480-76-2 5mg $750 2021-12-16 Buy
Product number Packaging Price Buy
J210403 2.5mg $2640 Buy
XJ161762 1mg $250 Buy
XJ161762 2mg $400 Buy
PXT0001950 5MG $505.59 Buy
XJ161762 5mg $750 Buy

JACOLINE Chemical Properties,Uses,Production

Description

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.

Uses

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).

References

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)

JACOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

JACOLINE Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Didu New Materials Co. Ltd
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Amadis Chemical Company Limited
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Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15185 58
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 7059 55
Biyu Biotechnology (Shanghai) Co., ltd 021-26018599 China 270 56
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012 sales@regentsciences.com China 9293 58
Nanjing Digger Medical Technology Co. Ltd. 025-025-51191215 18013836722 2399235533@qq.com China 4933 58
Sichuan BioCrick Biotech Co., Ltd 28-85433893 info@biocrick.com CHINA 4988 58
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14092 58
JACOLINE Jacolin (20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)- 480-76-2