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N-Desmethyl Regorafenib

CAS No.
1343498-72-5
Chemical Name:
N-Desmethyl Regorafenib
Synonyms
BAY751098;BAY 751098;BAY-751098;Relebactam D4;UNII-58I22S7HYD;Regorafenib impurity O;N-Desmethyl Regorafenib;Regorafenib Impurity 53;Regorafenib metabolite M4;Regorafenib M-4 metabolite
CBNumber:
CB63049901
Molecular Formula:
C20H13ClF4N4O3
Molecular Weight:
468.79
MDL Number:
MFCD34596810
MOL File:
1343498-72-5.mol
Last updated:2023-07-07 08:28:07

N-Desmethyl Regorafenib Properties

Melting point >195°C (dec.)
Boiling point 496.8±45.0 °C(Predicted)
Density 1.552±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka 12.06±0.70(Predicted)
form Solid
color Pale Orange to Pale Red
FDA UNII 58I22S7HYD

N-Desmethyl Regorafenib price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D293270 N-DesmethylRegorafenib 1343498-72-5 25mg $185 2021-12-16 Buy
Usbiological 458819 N-Desmethyl Regorafenib 1343498-72-5 1mg $460 2021-12-16 Buy
TRC D293270 N-DesmethylRegorafenib 1343498-72-5 250mg $1455 2021-12-16 Buy
Product number Packaging Price Buy
D293270 25mg $185 Buy
458819 1mg $460 Buy
D293270 250mg $1455 Buy

N-Desmethyl Regorafenib Chemical Properties,Uses,Production

Uses

N-Desmethyl Regorafenib is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.

757251-54-0
327-78-6
1343498-72-5
Synthesis of N-Desmethyl Regorafenib from 4-(4-AMino-3-fluorophenoxy)-pyridine-2-carboxylic acid aMide and 4-Chloro-3-(trifluoromethyl)phenyl isocyanate

N-Desmethyl Regorafenib Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 31)Suppliers
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TargetMol Chemicals Inc.
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Amadis Chemical Company Limited
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BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17994 56
Nanjing XiZe Biotechnology CO., Ltd. 025-58362220 15250997978 1511893459@qq.com China 7725 55
Roark Standards 0755-83552066 15986688328 service@roarkstandards.com China 1443 58
Tianjin shijia biomedical technology co., LTD 15022261580;411316762 tjshj1212@163.com China 2312 58
Shenzhen ruikai de biotechnology co., ltd. 0755-61348847 17820674378 2682116078@qq.com China 7844 58
Wuhan chuanghao Biotechnology Co., Ltd 13361917963 876725023@qq.com China 297 58
Cato Research Chemicals Inc. 020-81215950 4000-868-328 customer@uwalab.com United States 10413 58
N-Desmethyl Regorafenib Regorafenib impurity O Regorafenib N-Desmethyl Impurity Regorafenib M-4 metabolite 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]- Regorafenib metabolite M4 Regorafenib Impurity 53 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide Regorafenib M4 metabolite 13C6 BAY 751098 BAY751098 BAY-751098 UNII-58I22S7HYD Relebactam D4 1343498-72-5 C20H13ClF4N4O3