ChemicalBook >> CAS DataBase List >>AURINTRICARBOXYLIC ACID
AURINTRICARBOXYLIC ACID
- CAS No.
- 4431-00-9
- Chemical Name:
- AURINTRICARBOXYLIC ACID
- Synonyms
- ATA;SKL331;e)-6-oxo-;aluminonfreeacid;TIMTEC-BB SBB005410;AURINTRICARBONIC ACID;aurintricarboxylicaci;LABOTEST-BB LT00080677;AURINTRICARBOXYLIC ACID;aurinetricarboxylic acid
- CBNumber:
- CB7463004
- Molecular Formula:
- C22H14O9
- Molecular Weight:
- 422.34
- MDL Number:
- MFCD00011663
- MOL File:
- 4431-00-9.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:15
| Melting point | 300 °C(lit.) |
|---|---|
| Boiling point | 458.99°C (rough estimate) |
| Density | 1.3860 (rough estimate) |
| refractive index | 1.6230 (estimate) |
| storage temp. | +15C to +30C |
| solubility | 1 M NH4OH: 10 mg/mL |
| form | powder |
| pka | 2.20±0.20(Predicted) |
| color | dark red to brown |
| Water Solubility | Insoluble in water. |
| BRN | 2228904 |
| CAS DataBase Reference | 4431-00-9(CAS DataBase Reference) |
| FDA UNII | NP9O8E29QW |
| EPA Substance Registry System | Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy- (4431-00-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GU4790000 | |||||||||
| TSCA | Yes | |||||||||
| NFPA 704 |
|
AURINTRICARBOXYLIC ACID price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A1895 | Aurintricarboxylic acid practical grade, ≥85% (titration), powder | 4431-00-9 | 5g | $69.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 189400 | Aurintricarboxylic Acid | 4431-00-9 | 100mg | $56.2 | 2024-03-01 | Buy |
| Alfa Aesar | A15905 | Aurintricarboxylic acid | 4431-00-9 | 5g | $47 | 2024-03-01 | Buy |
| Alfa Aesar | A15905 | Aurintricarboxylic acid | 4431-00-9 | 25g | $128.65 | 2024-03-01 | Buy |
| Sigma-Aldrich | A1895 | Aurintricarboxylic acid practical grade, ≥85% (titration), powder | 4431-00-9 | 25g | $240 | 2024-03-01 | Buy |
AURINTRICARBOXYLIC ACID Chemical Properties,Uses,Production
Chemical Properties
deep red coarse crystalline powder
Uses
endonuclease inhibitor; apoptosis inhibitor, topoisomerase II inhibitor
Uses
Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.
Definition
ChEBI: A member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while the triammonium salt is 'aluminon'.
Purification Methods
The acid is dissolved in aqueous NaOH, NaHSO3 solution is added until the colour is discharged and then the tricarboxylic acid is precipitated with HCl. [Heisig & Lauer Org Synth Coll Vol I 54 1941, Beilstein 10 IV 4161]. Do not extract the acid with hot water because it softens, forming a viscous mass. Make a solution in aqueous NH3. Aluminon is the NH4 salt.
AURINTRICARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 121)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
View Lastest Price from AURINTRICARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | AURINTRICARBOXYLIC ACID
4431-00-9
|
US $1.00 / kg | 1kg | 95%-99% | 100kg | Career Henan Chemical Co | |
|
|
2019-07-06 | AURINTRICARBOXYLIC ACID
4431-00-9
|
US $1.00 / kg | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
-
- AURINTRICARBOXYLIC ACID
4431-00-9
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
-
- AURINTRICARBOXYLIC ACID
4431-00-9
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
4431-00-9(AURINTRICARBOXYLIC ACID)Related Search:
TIMTEC-BB SBB005410
LABOTEST-BB LT00080677
ATA
5,5-(3-carboxy-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylic acid)
aurinetricarboxylic acid
AURINTRICARBOXYLIC ACID FREE ACIDPRACTIC AL GRADE
Aurintricarboxylic Acid (Ata)
AURINTRICARBONIC ACID
Aurintricarboxylic acid, tech., 85%
1-Oxo-4-[bis(3-carboxy-4-hydroxyphenyl)methylene]-2,5-cyclohexadiene-2-carboxylic acid
5,5'-[(3-Carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis(2-hydroxybenzoic acid)
Aurintricarboxylic acid,85%,tech.
5,5'-((3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)Methylene)bis(2-hydroxybenzoic acid)
AURINTRICARBOXYLIC ACID
1,4-cyclohexadiene-1-carboxylicacid,3-(bis(3-carboxy-4-hydroxyphenyl)methylen
5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-benzoicaci
aluminonfreeacid
e)-6-oxo-
5,5'-((3-Carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)
bis(2-hydroxybenzoic acid)
Benzoic acid, 3,3'-[(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxy-
aurintricarboxylicaci
Aurintricarboxylic Acids (Technical Grade)
SKL331
5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid
Aurintricarboxylic Acid - CAS 4431-00-9 - Calbiochem
4431-00-9
C22H14O9
DNA metabolism
DNA Repair Regulators
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Apoptosis and Cell Cycle
Colours, Dyes, Indicators & Pigments