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EFONIDIPINE

EFONIDIPINE Structure
EFONIDIPINE structure
CAS No.
111011-63-3
Chemical Name:
EFONIDIPINE
Synonyms
EFONIDIPINE;Efonidipine(NZ-105);EFONIDIPINE FREE BASE;NZ105,Inhibitor,Ca channels,inhibit,Calcium Channel,NZ 105,Efonidipine,Ca2+ channels;2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate;2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate;5,5-Dimethyl-2-[[1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-[[2-[phenyl(phenylmethyl)amino]ethoxy]carbonyl]pyridin]-3-yl]-1,3,2-dioxaphosphorinane 2-oxide;5-(5,5-Dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-[phenyl(phenylmethyl)amino]ethyl ester;3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester
CBNumber:
CB92130511
Molecular Formula:
C34H38N3O7P
Molecular Weight:
631.66
MDL Number:
MFCD00865899
MOL File:
111011-63-3.mol
Last updated:2023-05-21 10:59:17
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EFONIDIPINE Properties

Melting point 169-170℃
Boiling point 746.9±60.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF:30.0(Max Conc. mg/mL);47.49(Max Conc. mM)
Ethanol:40.0(Max Conc. mg/mL);63.32(Max Conc. mM)
form A crystalline solid
pka 4.03±0.50(Predicted)
FDA UNII 40ZTP2T37Q

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H317-H319-H335-H360
Precautionary statements  P201-P261-P280-P305+P351+P338-P308+P313

EFONIDIPINE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0005025 EFONIDIPINE 95.00% 111011-63-3 10MG $224.7 2021-12-16 Buy
CSNpharm CSN16302 Efonidipine 111011-63-3 50mg $307 2021-12-16 Buy
DC Chemicals DC23624 Efonidipine >98% 111011-63-3 1g $1600 2021-12-16 Buy
Crysdot CD31004556 Efonidipine 98+% 111011-63-3 10mg $56 2021-12-16 Buy
Chemenu CM172430 2-(benzyl(phenyl)amino)ethyl5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 98% 111011-63-3 50mg $209 2021-12-16 Buy
Product number Packaging Price Buy
API0005025 10MG $224.7 Buy
CSN16302 50mg $307 Buy
DC23624 1g $1600 Buy
CD31004556 10mg $56 Buy
CM172430 50mg $209 Buy

EFONIDIPINE Chemical Properties,Uses,Production

Definition

ChEBI: 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate is a carboxylic ester resulting from the formal condensation of the carboxy group of 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid with the hydroxy group of 2-[benzyl(phenyl)amino]ethanol. It is a C-nitro compound, a carboxylic ester, a tertiary amino compound and a dihydropyridine.

EFONIDIPINE synthesis

111011-80-4
111011-63-3
Synthesis of EFONIDIPINE from 1-(5,5-DiMethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)propan-2-one

EFONIDIPINE Preparation Products And Raw materials

Raw materials

2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 3-(5,5-diMethyl-2-oxo-1,3,2-dioxaphorinane-2-yl)-4-(3-nitrophenyl)-bu-3-en-2-one 1-(5,5-DiMethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)propan-2-one 2,2-Dimethyl-1,3-propanediol

Preparation Products

EFONIDIPINE Suppliers

Global( 69)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com CHINA 52861 58
Hebei Duling International Trade Co. LTD 		+8617333973358 sales01@hbduling.cn China 15620 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
PT CHEM GROUP LIMITED 		+86-85511178 +86-85511178 peter68@ptchemgroup.com China 35453 58
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Hebei Duling International Trade Co. LTD 		58
LEAP CHEM CO., LTD. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
PT CHEM GROUP LIMITED 		58

View Lastest Price from EFONIDIPINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
EFONIDIPINE pictures 2019-12-26 EFONIDIPINE
111011-63-3
 US $1.00 / KG 1KG ≥98% g/kg/Ton Career Henan Chemical Co
  • EFONIDIPINE pictures
  • EFONIDIPINE
    111011-63-3
  • US $1.00 / KG
  • ≥98%
  • Career Henan Chemical Co

111011-63-3(EFONIDIPINE)Related Search:

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EFONIDIPINE 5-(5,5-Dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-[phenyl(phenylmethyl)amino]ethyl ester 5,5-Dimethyl-2-[[1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-5-[[2-[phenyl(phenylmethyl)amino]ethoxy]carbonyl]pyridin]-3-yl]-1,3,2-dioxaphosphorinane 2-oxide EFONIDIPINE FREE BASE Efonidipine(NZ-105) 2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 2-(N-benzylanilino)ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester NZ105,Inhibitor,Ca channels,inhibit,Calcium Channel,NZ 105,Efonidipine,Ca2+ channels 111011-63-3 Inhibitors