Carbenoxolone
- CAS No.
- 5697-56-3
- Chemical Name:
- Carbenoxolone
- Synonyms
- bioral;biogastrone;Carbenoxolon;CARBENOXOLONE;Carbenoxolona;CARBENOXOLONE [U;Carbenoxolone-d4;CARBENOXOLONE(RG);glycyrrhetnic acid;Carbenoxolone (YP 003)
- CBNumber:
- CB9314814
- Molecular Formula:
- C34H50O7
- Molecular Weight:
- 570.76
- MDL Number:
- MFCD20926283
- MOL File:
- 5697-56-3.mol
- MSDS File:
- SDS
| Melting point | 291-294 °C |
|---|---|
| alpha | D20 +128° (chloroform) |
| Boiling point | 553.75°C (rough estimate) |
| Density | 1.20 |
| refractive index | 1.5820 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | pKa 6.7 (Uncertain) |
| color | Cream crystals |
| Water Solubility | 6.621mg/L(24 ºC) |
| CAS DataBase Reference | 5697-56-3(CAS DataBase Reference) |
| FDA UNII | MM6384NG73 |
| ATC code | A02BX01 |
| EPA Substance Registry System | Olean-12-en-29-oic acid, 3-(3-carboxy-1-oxopropoxy)-11-oxo-, (3.beta.,20.beta.)- (5697-56-3) |
Carbenoxolone price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C175903 | Carbenoxolone | 5697-56-3 | 500mg | $60 | 2021-12-16 | Buy |
| TRC | C175903 | Carbenoxolone | 5697-56-3 | 1g | $70 | 2021-12-16 | Buy |
| Matrix Scientific | 076221 | (3Beta,20beta)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid 95+% | 5697-56-3 | 5g | $120 | 2021-12-16 | Buy |
| Matrix Scientific | 076221 | (3Beta,20beta)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid 95+% | 5697-56-3 | 10g | $179 | 2021-12-16 | Buy |
| AK Scientific | W7055 | Carbenoxolone | 5697-56-3 | 5g | $212 | 2021-12-16 | Buy |
Carbenoxolone Chemical Properties,Uses,Production
Originator
Biogastrone,Winthrop,UK,1963
Uses
Glucocorticoid.
Manufacturing Process
23.5 g of glycyrrhetinic acid were dissolved in 50 cc of dry pyridine. A solution
of 6.0 g of succinic anhydride in 30 cc of dry pyridine was added, followed by
30 cc of dry triethylamine and then, for washing purposes, 5 cc of dry
pyridine. The solution was heated on a boiling water bath for ten hours and
then poured into excess of dilute hydrochloric acid and ice. The fine gray
precipitate formed was filtered off, washed with water, dissolved in chloroform,
and the solution repeatedly extracted with dilute hydrochloric acid and later
with water. It was dried over sodium sulfate and evaporated to dryness.
Crystallization from methanol, using charcoal to effect decolorization, gave the
hydrogen succinate as cream-colored crystals, MP 291° to 294°C, with
previous softening.
One molecular proportion of glycyrrhetinic acid hydrogen succinate was
ground with a dilute (5%) aqueous solution containing two molecular
proportions of sodium hydroxide. The solution was filtered and evaporated in
vacuum over concentrated sulfuric acid. The sodium salt is then obtained as a
creamy white water-soluble solid. Glycyrrhetinic acid is obtainable from
licorice root.
Therapeutic Function
Antiinflammatory (gastric)
Safety Profile
Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion andsubcutaneous routes. Human systemic effects byingestion: muscle weakness and flaccid paralysis. Whenheated to decomposition it emits acrid smoke and fumes.
Carbenoxolone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12468 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21688 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8829 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3082 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27945 | 58 |
View Lastest Price from Carbenoxolone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | Carbenoxolone
5697-56-3
|
US $15.00 / kg | 1kg | 99.912% | 10ton | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2023-09-19 | Carbenoxolone
5697-56-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-07-01 | Carbenoxolone
5697-56-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Carbenoxolone
5697-56-3
- US $15.00 / kg
- 99.912%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Carbenoxolone
5697-56-3
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Carbenoxolone
5697-56-3
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd