MYOSMINE
- CAS No.
- 532-12-7
- Chemical Name:
- MYOSMINE
- Synonyms
- Pyridine, 3-(3,4-dihydro-2H-pyrrol-5-yl)-;MYOSIME;yosmine;MYSOMINE;MYOSMINE;Myosming;Brn 0119254;MYOSMINE(RG);WIDELY MYOSMINE;Nicotine EP Impurity D
- CBNumber:
- CB9354452
- Molecular Formula:
- C9H10N2
- Molecular Weight:
- 146.19
- MDL Number:
- MFCD00052019
- MOL File:
- 532-12-7.mol
- MSDS File:
- SDS
| Melting point | 42-44°C |
|---|---|
| Boiling point | 82-83°C 0,5mm |
| Density | 1.12±0.1 g/cm3(Predicted) |
| Flash point | 82-83°C/0.5mm |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly), Water (Sparingly) |
| form | Solid |
| pka | pK1:5.26 (25°C) |
| color | Light Beige to Dark Yellow |
| BRN | 119254 |
| Stability | Moisture, Temperature Sensitive |
| LogP | 0.730 (est) |
| CAS DataBase Reference | 532-12-7(CAS DataBase Reference) |
| FDA UNII | 9O0A545W4L |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UT7660000 | |||||||||
| HazardClass | IRRITANT, IRRITANT-HARMFUL | |||||||||
| HS Code | 29399990 | |||||||||
| NFPA 704 |
|
MYOSMINE price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M8765 | Myosmine ≥98% | 532-12-7 | 100mg | $112 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR3062 | Nicotine Related Compound D certified reference material, pharmaceutical secondary standard | 532-12-7 | 50MG | $507 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1463359 | Myosmine | 532-12-7 | 20mg | $1450 | 2024-03-01 | Buy |
| Alfa Aesar | L11886 | Myosmine, 98%, may contain up to 2% water | 532-12-7 | 100mg | $78 | 2024-03-01 | Buy |
| Alfa Aesar | L11886 | Myosmine, 98%, may contain up to 2% water | 532-12-7 | 500mg | $282 | 2024-03-01 | Buy |
MYOSMINE Chemical Properties,Uses,Production
Description
The alkaloids found in tobacco smoke may be separated into those which are volatile in steam and those which are non-volatile. Myosmine occurs in the former group and, although only present in small quantities, is the most fully investigated of these bases. The alkaloid is normally obtained as an oily liquid which may be crystallized. It is optically inactive and readily soluble in light petroleum or Et20. It forms a hydrochloride as a microcrystalline powder which, on sublimation yields colourless rods, m.p. ISS-8°C. The dihydrochloride, also a microcrystalline powder, yields colourless needles on sublimation, m.p. 1S0- 17 Soc. The base also furnishes a dipicrate, m.p. 182-3°C (dec.) and a dipi_x0002_crolonate, m.p. 204°C (dec.). On dehydrogenation it gives 2-(3'-pyridyl)-pyrrole (picrate, m.p. 200°C) identical with that obtained in a similar manner from nornicotine. According to Woodward and his colleagues, the alkaloid is one of several products formed when nicotine is dehydrogenated over prepared quartz at S70°C. It is readily hydrolyzed in H20 to yield 3-pyridyl-r-aminopropyl ketone, forming a crystalline phenylhydrazone, m.p. 20l-2°C.
Chemical Properties
Light Yellow Powder
Uses
Tobacco alkaloid
Reactant for:
Nitrosation reactions
Peroxidation reaction with hydrogen peroxide
Uses
mitogen
Uses
Myosmine is an alkaloid found in tobacco. Myosmine has been suspected to be a tobacco-independent carcinogenic source.
Definition
ChEBI: Myosmine is a member of the class of pyridines that is pyridine substituted by a 3,4-dihydro-2H-pyrrol-5-yl group at position 3. It is an alkaloid found in tobacco plants and exhibits genotoxic effects. It has a role as a plant metabolite, an EC 1.14.14.14 (aromatase) inhibitor and a mutagen. It is a pyrroline and a pyridine alkaloid.
Synthesis Reference(s)
Canadian Journal of Chemistry, 35, p. 651, 1957 DOI: 10.1139/v57-094
The Journal of Organic Chemistry, 37, p. 1635, 1972
Tetrahedron Letters, 8, p. 5185, 1967
References
Spath, Wenusch, Zajic., Ber., 69, 393 (1936)
Woodward, Eisner, Haines., ibid, 69, 7S7 (1936)
Spath, Wibaut, Kesztler., ibid, 71, 100 (1938)
MYOSMINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12468 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8829 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6708 | 58 |
View Lastest Price from MYOSMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-22 | Myosmine
532-12-7
|
US $1.00 / KG | 1KG | 99.91% | 200000 | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2023-06-26 | MYOSMINE
532-12-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2022-02-25 | Myosmine
532-12-7
|
US $2.30 / Kg/Bag | 100g | 99% | 20tons | Hong Kong Tiansheng New Material Trading Co., Ltd |
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