カルグトシン

カルグトシン 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

カルグトシン 化学特性,用途語,生産方法

効能

分娩誘発薬, オキシトシン受容体作動薬

Originator

Statocin,Yoshitomi,Japan,1982

Manufacturing Process

To a suspension of Z-Tyr(Bz)-Ile-Gln-Asn-Asu(OTCP)-Gly-Leu-Gly-NH2 (1,310 mg) in DMF (350 ml) is added a suitable amount of palladium black. Hydrogen gas is introduced with stirring at room temperature (25°C) for about 40 hours. After stirring the mixture at 30°-35°C for several hours, the catalyst is filtered off and the filtrate is concentrated under reduced pressure. A large amount of ether is added to the residue, and the white coagulum is collected by filtration, washed with ether and dried. This is dissolved in water (30 ml), and the solution is filtered. The filtrate is passed through a column (3 x 11.5 cm) of Amerlite IR-45 (OH-form). The fractions which show a UV-absorption maximum at 280 nm are combined and passed through a column (3 x 125 cm) of CM-Sephadex C-25 to remove the noncyclic compound and obtain neutral parts. The detection of the objective compound is made by UV_x0002_absorption at 280 nm. The aqueous solution of the neutral parts is concentrated below 35°C, under reduced pressure, and the concentrate is lyophilized to give 504 mg of the crude title compound in the form of 5 hydrate.

Therapeutic Function

Oxytocic

カルグトシン 上流と下流の製品情報

原材料

準備製品

カルグトシン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9126	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

33605-67-3(カルグトシン)キーワード:

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• 33605-67-3
• Cargutocin
• 1-Butyryl-7-glycyl-1,6-dicarbaoxytocin
• Butyryl(1)-L-Tyr-L-Ile-L-Gln-L-Asn-L-Abu(1)-Gly-L-Leu-Gly-NH2
• Statogin
• Y-5350
• (2S,5S,8S,11S)-5-[(2S)-butan-2-yl]-8-(2-carbamoylethyl)-11-(carbamoylmethyl)-N-[[(1S)-1-(carbamoylmethylcarbamoyl)-3-methyl-butyl]carbamoylmethyl]-2-[(4-hydroxyphenyl)methyl]-3,6,9,12,20-pentaoxo-1,4,7,10,13-pentazacycloicosane-14-carboxamide
• Glycinamide, L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-(2S)-7-carboxyheptanoylglycyl-L-leucyl-, (5→1)-lactam
• Cargutocin USP/EP/BP
• シントシン
• カルグトシン
• スタトギン
• グルカトシン
• ブチリル(1)-L-Tyr-L-Ile-L-Gln-L-Asn-L-Abu(1)-Gly-L-Leu-Gly-NH2
• 1-ブチリル-7-グリシル-1,6-ジカルバオキシトシン
• カルグトシン (JAN)
• (2S)-2-(2-{[(2S,5S,8S,11S,14S)-5-[(2S)-ブタン-2-イル]-8-(2-カルバモイルエチル)-11-(カルバモイルメチル)-2-[(4-ヒドロキシフェニル)メチル]-3,6,9,12,20-ペンタオキソ-1,4,7,10,13-ペンタアザシクロイコサン-14-イル]ホルムアミド}アセトアミド)-N-(カルバモイルメチル)-4-メチルペンタンアミド