キニン·塩酸塩

キニン·塩酸塩 化学構造式
130-89-2
CAS番号.
130-89-2
化学名:
キニン·塩酸塩
别名:
(8α,9R)-6'-メトキシシンコナン-9-オール·塩酸塩;塩酸キニーネ;キニン·塩酸塩;キニン·塩酸;キニン塩酸塩;キニーネ·塩酸塩;キニーネHCl
英語名:
Quinine hydrochloride
英語别名:
QUININE HC;QUININE HCL;chinimetten;quininemuriate;quininechloride;Quinine Impurity 11;Quinine hydrochlorid;QUININE HYDROCHLORIDE;Quinine HCL & Sulfate;QUININE HCL USP/EP/BP
CBNumber:
CB2453521
化学式:
C20H25ClN2O2
分子量:
360.88
MOL File:
130-89-2.mol

キニン·塩酸塩 物理性質

融点 :
158-160 C
比重(密度) :
1.1206 (rough estimate)
屈折率 :
1.5400 (estimate)
FEMA :
2976 | QUININE HYDROCHLORIDE
貯蔵温度 :
under inert gas (nitrogen or Argon) at 2-8°C
溶解性:
DMSO(微量)、エタノール(微量)
外見 :
個体
色:
白い
水溶解度 :
549.7mg/L(25℃)
InChIKey:
LBSFSRMTJJPTCW-QJLYHTAINA-N
SMILES:
C12C=C(C=CC=1N=CC=C2[C@@H](O)[C@]1([H])C[C@]2([H])CCN1C[C@@H]2C=C)OC.Cl |&1:10,12,15,21,r|
LogP:
3.496 (est)
EPAの化学物質情報:
Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8.alpha.,9R)- (130-89-2)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  Xi
Rフレーズ  36/37/38
Sフレーズ  26-36-24/25
RIDADR  1544
国連危険物分類  6.1(b)
容器等級  III
HSコード  29392000
毒性 cat,LDLo,intravenous,80mg/kg (80mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 327, 1927.
絵表示(GHS) GHS hazard pictograms
注意喚起語 警告
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H302 飲み込むと有害 急性毒性、経口 4 警告 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
注意書き
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

キニン·塩酸塩 価格 もっと(6)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-6911
Quinine HCl
130-89-2 1g ¥10000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-6911
Quinine HCl
130-89-2 5g ¥10000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-6911
Quinine HCl
130-89-2 25g ¥19000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-6911
Quinine HCl
130-89-2 100g ¥60000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC4114
Quinine hydrochloride
130-89-2 50mg ¥18000 2023-06-01 購入

キニン·塩酸塩 化学特性,用途語,生産方法

用途

香料・香辛料

化学的特性

Quinine hydrochloride is a white, silky, glittering needles; odourless, effloresces when exposed to warm air. Soluble in water, very soluble in ethanol, freely soluble in chloroform, insoluble in ether. Its solutions are neutral or alkaline to litmus. It is an alkaloid derived from the bark of the cinchona tree. Quinine Hydrochloride is used as ingredient of beverages and injection medication.

使用

Quinine Hydrochloride is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

定義

Quinine Hydrochloride is the hydrochloride of a natural substance, quinine, obtained from the bark of various species of Cinchona including Cinchona succirubra, Pavon. (red cinchona); Cinchona officinalis, Linn; Cinchona calizaya, Wenddell; Cinchona ledgeriana, Moens. It is a nature-derived bitter flavoring agent for tonic water, among other beverages.

生物活性

Quinine hydrochloride is a displays antimalarial and muscle relaxant properties. Stereoisomer of quinidine; closely related to chloroquine.?

安全性プロファイル

Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Human systemic effects by intravenous route: convulsions or effect on seizure threshold, muscle contraction or spasticity, and nausea or vomiting. Mutation data reported. Used as a local anesthetic. When heated to decomposition it emits very toxic fumes of NO, and HCI. See also QUININE.

キニン·塩酸塩 上流と下流の製品情報

原材料

準備製品


キニン·塩酸塩 生産企業

Global( 185)Suppliers
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キニン·塩酸塩  スペクトルデータ(1HNMR、13CNMR、IR1、Raman)


130-89-2(キニン·塩酸塩)キーワード:


  • 130-89-2
  • QUININE HCL
  • QUININE HYDROCHLORIDE
  • QUININE MONOHYDROCHLORIDE
  • 6’-methoxy-,monohydrochloride,(8.alpha.,9R)-Cinchonan-9-ol
  • 6’-methoxy-,monohydrochloride,(8-alpha,9r)-cinchonan-9-o
  • 6’-methoxy-,monohydrochloride,(8alpha,9theta)-cinchonan-9-o
  • chinimetten
  • quininechloride
  • quininemuriate
  • Hydrochloric acid quinine
  • Quinine·hydrochloric acid
  • Quinine HCL & Sulfate
  • Cinchonan-9-ol,6'-Methoxy-, hydrochloride (1:1), (8alpha,9R)-
  • (8alpha,9R)-6'-methoxycinchonan-9-ol monohydrochloride
  • QUININE HYDROCHLORIDE 2 H2O
  • Cinchonan-9-ol, 6-methoxy-, monohydrochloride, (8.alpha.,9R)-
  • Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8a,9R)- (9CI)
  • Quinine, monohydrochloride (8CI)
  • (R)-[(4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol:hydrochloride
  • Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8α,9R)-
  • Quinine Hydrochloride HCL
  • QUININE HCL USP/EP/BP
  • (R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride
  • Quinine hydrochlorid
  • (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol hydrochloride
  • QUININE HC
  • Quinine Impurity 11
  • Cyproconazole Impurity 3
  • (8α,9R)-6'-メトキシシンコナン-9-オール·塩酸塩
  • 塩酸キニーネ
  • キニン·塩酸塩
  • キニン·塩酸
  • キニン塩酸塩
  • キニーネ·塩酸塩
  • キニーネHCl
  • 抗マラリア薬
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