ペンタガスリン

ペンタガスリン 価格 もっと(9)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01BCS4002096	ペンタガスリン Pentagastrin	5534-95-2	25mg	￥32000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01BCS4002096	ペンタガスリン Pentagastrin	5534-95-2	100mg	￥95000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	BP278	ペンタガストリン British Pharmacopoeia (BP) Reference Standard British Pharmacopoeia (BP) Reference Standard	5534-95-2	5mg	￥33600	2024-03-01	購入
Sigma-Aldrich Japan	B1636	ペンタガストリン ≥95% (HPLC), powder Pentagastrin ≥95% (HPLC), powder	5534-95-2	25mg	￥52500	2024-03-01	購入
Sigma-Aldrich Japan	B1636	ペンタガストリン ≥95% (HPLC), powder Pentagastrin ≥95% (HPLC), powder	5534-95-2	100mg	￥167000	2024-03-01	購入

ペンタガスリン 化学特性,用途語,生産方法

効能

診断補助薬 (胃酸分泌指標)

説明

Pentagastrin is a synthetic polypeptide and cholecystokinin-2 (CCK₂) receptor agonist. It binds selectively to CCK₂ receptors in guinea pig brain over CCK₁ receptors in rat pancreas (IC₅₀s = 11 and 1,100 nM, respectively). Pentagastrin increases calcium influx and polyphosphoinositide turnover in rat GH3 pituitary cells (EC₅₀s = 23 and 3.9 nM, respectively). It also increases histidine decarboxylase activity in mucous- and endocrine cell-enriched isolated rabbit fundic mucosal cells (EC₅₀ = 2.9 nM). Pentagastrin induces contraction of isolated pig ileum smooth muscle cells in vitro (EC₅₀ = 30 pM). It increases gastric acid and pepsin secretion in conscious cats in vivo (ED₅₀s = 1.29 and 57.3 nmol/kg² per hour, respectively). Formulations containing pentagastrin have previously been used as a diagnostic aid to evaluate gastric acid secretory function.

化学的特性

A white or almost white powder.

使用

Pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid as the pentagastrin-stimulated calcitonin test.

一般的な説明

Pentagastrin (Peptavlon), a physiologicalgastric acid secretagogue, is the synthetic pentapeptide derivative:N-t-butyloxycarbonyl-β-alanyl-L-tryptophyl-L-methionyl-L-aspartyl-L-phenylalanyl amide. It contains theCOOH-terminal tetrapeptide amide (H·Try·Met· Asp·Phe·NH₂), which is considered to be the active center ofthe natural gastrins. Accordingly, pentagastrin appears tohave the physiological and pharmacological properties ofthe gastrins, including stimulation of gastric secretion,pepsin secretion, gastric motility, pancreatic secretion ofwater and bicarbonate, pancreatic enzyme secretion, biliaryflow and bicarbonate output, intrinsic factor secretion, andcontraction of the gallbladder.
Pentagastrin is indicated as a diagnostic agent to evaluategastric acid secretory function, and it is useful in testing foranacidity in patients with suspected pernicious anemia, atrophicgastritis or gastric carcinoma, hypersecretion in suspectedduodenal ulcer or postoperative stomal ulcers, andZollinger-Ellison tumor.

ペンタガスリン 上流と下流の製品情報

原材料

準備製品

ペンタガスリン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Shanghai Getian Industrial Co., LTD	+86-15373193816 +86-15373193816	mike@ge-tian.com	China	274	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55
Rixing Chemical CO.,LTD	+86-13237129059 -13237129059	sales@rixingchemi.com	CHINA	229	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Beijing Yibai Biotechnology Co., Ltd	0086-182-6772-3597	sales04@yibaibiotech.com	CHINA	419	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9126	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28557	58

5534-95-2(ペンタガスリン)キーワード:

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• 5534-95-2
• T-BOC-BETA-ALA-TRP-MET-ASP-PHE-NH2
• aspartyl]-l-phenylalaninamide
• ay6608
• boc-beta-ala-try-met-asp-phe(nh2)
• gastrodiagnost
• ici50123
• lanineamide
• l-methionyl-l-alpha-aspartyl-
• l-n-tert-butyleste
• n-((1,1-dimethylethoxy)carbonyl)-beta-alanyl-l-tryptophyl-l-phenylalaninamid
• petogasrin
• -tert-butylester
• ylpropionamido]-4-(methylthio)butyramido]succinamicacidn-tert-butylester
• n-t-boc-β-ala-trp-met-asp-phe amide
• N-T-boc-B-ala-trp-met-asp-phe amide
• PENTAGASTRIN (ICI 50123) SYNTHETIC >99%
• BOC-β-Ala-Trp-Met-Asp-Phe-NH2
• N-(1,1-Dimethylethoxy)carbonyl-βAla-L-Trp-L-Met-L-Asp-L-Phe-NH2
• N-Boc-βAla-L-Trp-L-Met-L-Asp-L-Phe-NH2
• AY 6608, ICI 50123, NSC 367746, Boc-(b-Ala13)-Gastrin (13-17), Boc-b-Ala-CCK-4
• Boc-b-Ala-Trp-Met-Asp-Phe-NH2
• n-(alpha-carbamoylphenethyl)-3-[2-[2-[3-(carboxyamino)propionamido]-3-indol-3-
• n-[n-[n-[n-(n-tert-butoxycarbonyl-beta-alanyl)-l-tryptophanyl]-l-methionyl]-l-
• n-carboxy-beta-alanyl-l-tryptophyl-l-methionyl-l-aspartylphenyl-alaninamid
• n-carboxy-beta-alanyl-l-tryptophyl-l-methionyl-l-aspartylphenyl-l-alaninamiden
• n-t-butyloxycarbonyl-beta-alanyl-l-tryptophyl-l-methionyl-l-aspartyl-l-phenyla
• peptavlon
• petavlon
• Boc-(β-Ala13)-Gastrin (13-17)
• GRP
• N-(1,1-ジメチルエトキシ)カルボニル-βAla-L-Trp-L-Met-L-Asp-L-Phe-NH2
• ペンタガストリン
• ペプタブロン
• ペンタガスリン
• ペンタガストリン (JAN)
• (3S)-3-[(2S)-2-[(2S)-2-(3-{[(tert-ブトキシ)カルボニル]アミノ}プロパンアミド)-3-(1H-インドール-3-イル)プロパンアミド]-4-(メチルスルファニル)ブタンアミド]-3-{[(1S)-1-カルバモイル-2-フェニルエチル]カルバモイル}プロパン酸