GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE

GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE 구조식 이미지
카스 번호:
217082-58-1
상품명:
GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
동의어(영문):
APELIN-13;QRPRLSHKGPMPF;PREPRO-65-77-APELIN;Apelin (1-13) (human);APELIN-13 (HUMAN, BOVINE);apelin-13 trifluoroacetate salt;APELIN-13 (HUMAN, BOVINE, MOUSE, RAT);Apelin-13 trifluoroacetate salt >=95%;Apelin-13, human, bovine, mouse, rat (2);GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
CBNumber:
CB0671552
분자식:
C69H111N23O16S
포뮬러 무게:
1550.83
MOL 파일:
217082-58-1.mol

GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE 속성

밀도
1.50±0.1 g/cm3(Predicted)
저장 조건
−20°C
용해도
PBS(pH 7.2)에 약 10mg/ml로 용해됩니다.
물리적 상태
동결건조된 분말
산도 계수 (pKa)
3.56±0.10(Predicted)
시퀀스
H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH

안전

WGK 독일 3

GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE C화학적 특성, 용도, 생산

용도

The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively). Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM (the EC50 values for apelin-17 and apelin-36 are 2.5 and 20 nM, respectively). It acts primarily in the periphery and central nervous system, playing important roles in regulating cardiovascular function, fluid homeostasis, hypertension, and insulin sensitivity. Unlike apelin-36, apelin-13 poorly blocks the entry of human immunodeficiency virus into cells.

일반 설명

Apelin is a regulatory peptide and a ligand of the APJ receptor. It is a member of the G protein-coupled receptor family. Apelin and APJ are broadly dispersed in the body.

Biochem/physiol Actions

Apelin plays physiological roles in the cytoprotection of many internal organs. It is used to treat insulin resistance and hypertension, but it may also can act as a negative factor. Apelin also regulates cardiovascular diseases.

GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE 준비 용품 및 원자재

원자재

준비 용품


GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE 공급 업체

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Zhejiang J&C Biological Technology Co.,Limited
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Hangzhou Go Top Peptide Biotech
0571-88211921
sales1@gotopbio.com CHINA 2609 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58

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