2',3',5'-Tri-O-acetyluridine
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2',3',5'-Tri-O-acetyluridine 속성
- 녹는점
- 127.0 to 131.0 °C
- 밀도
- 1.43±0.1 g/cm3(Predicted)
- 저장 조건
- Inert atmosphere,Store in freezer, under -20°C
- 용해도
- 클로로포름(약간 용해됨), 디클로로메탄(약간 용해됨), DMSO(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 9.39±0.10(Predicted)
- 색상
- 회백색
- InChI
- InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1
- InChIKey
- AUFUWRKPQLGTGF-QRMSVCKNSA-N
- SMILES
- C(OC(=O)C)[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC(=O)C)[C@@H]1OC(=O)C
- CAS 데이터베이스
- 4105-38-8(CAS DataBase Reference)
안전
안전지침서 | 24/25 | ||
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WGK 독일 | 3 | ||
HS 번호 | 29349990 | ||
기존화학 물질 | KE-35245 |
2',3',5'-Tri-O-acetyluridine C화학적 특성, 용도, 생산
개요
Uridine triacetate is an orally available pro-drug of uridine approved by the FDA for the treatment of the rare autosomal recessive disorder called hereditary orotic aciduria. The drug was also approved for treating overdose of two chemotherapies (fluorouracil and capecitabine). Uridine triacetate was developed by Wellstat Therapeutics and licensed to BTG.화학적 성질
White or almost white crystalline powder용도
2’,3’,5’-Triacetyluridine is used in the treatment of Alzheimer’s disease in mice and provide neuroprotective effects. Shown to also decrease depressive symptoms and increases in brain pH bipolar patients.정의
ChEBI: Uridine triacetate is an acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. It has a role as a prodrug, a neuroprotective agent and an orphan drug. It is a member of uridines and an acetate ester.2',3',5'-Tri-O-acetyluridine 준비 용품 및 원자재
원자재
준비 용품
2',3',5'-Tri-O-acetyluridine 공급 업체
글로벌( 304)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 |
sales1@nuowei-chem.com | China | 1642 | 58 |
Hangzhou Measure Life Technology Co., LTD | +8613343730176 |
2924244016@qq.com | China | 83 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
Hebei Duling International Trade Co. LTD | +8617333973358 |
sales01@hbduling.cn | China | 15620 | 58 |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 3001 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15954 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21687 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
2',3',5'-Tri-O-acetyluridine 관련 검색:
5-플루오로-2'-디옥시유리딘 우라실 디에틸렌글리콜디아세테이트 우리딘 2-(1-메톡시에톡시)에틸 아세테이트 디옥시우리딘
1-beta-D-Arabinofuranosyluracil
Doxifluridine
Sodium triacetoxyborohydride
Trifluridine
2',3',5'-Triacetylguanosine
uridine diphosphate glucose {= UDP-glucose}
2',3',5'-TRI-O-BENZOYLURIDINE
Diethyleneglycol diformate
2'-O-Methyluridine
TETRAHYDROFURFURYL ACETATE
3'-DEOXYURIDINE
1-amino-3-methoxy-propan-2-ol