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루타마이신

루타마이신 구조식 이미지

카스 번호:: 1404-59-7

한글명:: 루타마이신

동의어(한글):: 루타마이신

상품명:: Rutamycin

동의어(영문):: A-272;RR-32705;Rutamycin;RRNo-32705;oligomycin D;26-Demethyloligomycin A;RutaMycin, 26-deMethyloligoMycin A, A 272, RR 32705, RutaMycin A;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-,(1S,2'R,4E,5'S,6S,6'S,7S,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-, (1S,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-

CBNumber:: CB11120704

분자식:: C44H72O11

포뮬러 무게:: 777.042

MOL 파일:: 1404-59-7.mol

속성

안전

용도

공급 업체 36

루타마이신 속성

녹는점: 116-119°

알파: D20 -62° (c = 1.36 in CHCl3)

끓는 점: 883.4±65.0 °C(Predicted)

밀도: 1.15±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble

물리적 상태: A lyophilisate

산도 계수 (pKa): 12.52±0.70(Predicted)

안전

유엔번호(UN No.)	2811
위험 등급	6.1(b)
포장분류	III
독성	LD50 oral in mouse: 800mg/kg

루타마이신 C화학적 특성, 용도, 생산

개요

Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F₁F_O-ATPase and is used to uncouple oxidative phosphorylation from electron transport. Oligomycin D is reported to inhibit K-Ras plasma membrane localization in MDCK cells with an IC₅₀ value of 3.49 nM and is cytotoxic to SW620 colon cancer cells with an IC₅₀ value of 36 μM.

용도

Oligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane. Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.

루타마이신 준비 용품 및 원자재

원자재

준비 용품

루타마이신 공급 업체

글로벌( 36)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+86-19164747840 +86-13119157289	13119157289@163.com	China	2971	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55954	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58

루타마이신 관련 검색:

Chloramphenicol Natamycin OLIGOMYCIN Rutamycin