macbecin I
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macbecin I 속성
- 녹는점
- 205-206 °C(Solv: ethanol (64-17-5); water (7732-18-5))
- 끓는 점
- 736.2±60.0 °C(Predicted)
- 밀도
- 1.17±0.1 g/cm3(Predicted)
- 저장 조건
- Desiccate at -20°C
- 용해도
- Soluble in DMSO > 10 mM
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 8.62±0.70(Predicted)
안전
macbecin I C화학적 특성, 용도, 생산
용도
Macbecin I is an ansamycin antibiotic inhibitor of Hsp90 activity.생물학적 활성
Ansamycin antibiotic compound that inhibits Hsp90 activity (IC 50 = 2 μ M) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC 50 ~ 0.4 μ M) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher affinity and potency than geldanamycin (9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-carbamate ).macbecin I 준비 용품 및 원자재
원자재
준비 용품
macbecin I 공급 업체
글로벌( 23)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24018 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 8740 | 58 |
| ApexBio Technology | -- |
sales@apexbt.com | United States | 6254 | 58 |