Ryanodine
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Ryanodine 속성
- 알파
- D25 +26° (methanol)
- 끓는 점
- 586.95°C (rough estimate)
- 밀도
- 1.2805 (rough estimate)
- 굴절률
- 1.6000 (estimate)
- 저장 조건
- Sealed in dry,2-8°C
- 용해도
- DMSO: 용해성10mg/mL, 투명
- 물리적 상태
- 흰색 고체
- 녹는점
- 219-220 °C
- 산도 계수 (pKa)
- 10.66±0.70(Predicted)
- 색상
- 흰색에서 베이지색
- CAS 데이터베이스
- 15662-33-6
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,N | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 21/22-50/53 | ||
| 안전지침서 | 36/37-60-61 | ||
| 유엔번호(UN No.) | UN 3077 9/PG 3 | ||
| RTECS 번호 | VM4025000 |
| 그림문자(GHS): |
 
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| 신호 어: | Warning | ||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Ryanodine C화학적 특성, 용도, 생산
개요
Ryania insecticide is the ground stem wood of the tropical tree Ryania speciosa Vahl., and it contains over a dozen of several structurally related alkaloids. Nowadays, this botanical preparation is of minor importance, but one of its major ingredients, ryanodine, is a widely used pharmacological tool in studies of the calcium release channels in sarcoplasmic reticulum membranes of skeletal and cardiac muscle of both insects and mammals (11,12).화학적 성질
white to off-white solid용도
Ryanodine is a potent inhibitor of Ca2+ release from sarcoplasmic reticulum with potential application towards the treatment of huntingtons disease.정의
ChEBI: An insecticide alkaloid isolated from South American plant Ryania speciosa.생물학적 활성
Potent inhibitor of Ca 2+ release from sarcoplasmic reticulum (IC 50 values are 10 and 2.8 nM in skeletal and cardiac muscle respectively).참고 문헌
Rogers et ai., J. Amer. Chem. Soc., 70, 3086 (1948)Kelly, Whittingham, Wusner., Chem. Ind., 857 (1952)
Structure:
Wiesner, Valenta, Findlay., Tetrahedron Lett., 221 (1967)
Hollstein, Rapoport.,J. Amer. Chem. Soc., 90,3864 (1968)
Wong, Hollstein, Rapoport., ibid, 90, 3866 (1968)
Wiesner., Collect. Czech. Chem. Commun., 33, 2656 (1968)
Crystal structure:
Srivastava, Przybylska., Can. J. Chem., 46,795 (1968)
Ryanodine 준비 용품 및 원자재
원자재
준비 용품
Ryanodine 공급 업체
글로벌( 113)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 94838 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| Ascent Scientific | 4401179829988 |
customerservice@ascentscientific.co.uk | United Kingdom | 279 | 60 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 |
marketing@targetmol.com | China | 7854 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 |
3003855609@qq.com | China | 7892 | 56 |
| Biyu Biotechnology (Shanghai) Co., ltd | 021-26018599 |
China | 270 | 56 |
Ryanodine 관련 검색:
1,4-시클로헥산디메탄올 시클로옥탄올 사이클로도데칸-1,2-디올
CYCLODODECYL FORMATE
CYCLODODECANE
CYCLOOCTANEMETHANOL
2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL
Ryanodine
trans-1,2-Cyclopentanediol
CYCLODODECYLMETHYL ETHER
CIS-1,2-CYCLOOCTANEDIOL
(1S)-TRANS-1,2-CYCLOPENTANEDIOL
(1R)-TRANS-1,2-CYCLOPENTANEDIOL MONOACETATE
(3S,5S)-2,6-Dimethyl-3,5-heptanediol
(R,R)-(-)-1,2-CYCLODODECANEDIOL
CIS-P-MENTHANE-3,8-DIOL
3-Deoxyryanodol
(S,S)-(+)-1,2-CYCLODODECANEDIOL