Triptorelin
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Triptorelin 속성
- 녹는점
- >180°C (dec.)
- 알파
- D23 -58.8° (c = 0.33 in acetic acid)
- 밀도
- 1.52±0.1 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- 알칼리성 용액 (약간 용해됨), 메탄올(매우 소량, 가열, 초음파 처리)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 9.82±0.15(Predicted)
- 색상
- 흰색에서 황백색까지
- 안정성
- 흡습성
- InChIKey
- HPPONSCISKROOD-OYLNGHKZSA-N
- CAS 데이터베이스
- 57773-63-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T | ||
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위험 카페고리 넘버 | 60 | ||
안전지침서 | 53-22-36/37/39-45 | ||
WGK 독일 | 3 | ||
HS 번호 | 2937190000 |
그림문자(GHS): | |||||||||||||||
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신호 어: | Danger | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Triptorelin C화학적 특성, 용도, 생산
개요
Decapeptyl is a modified (D-Trp6) LH-RH. Like recently marketed buserelin and leuprolide (I), it is useful in achieving medical castration in the treatment of advanced prostate cancer.용도
Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferation.정의
ChEBI: An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone.Clinical Use
Triptorelin pamoate is another superagonist of GnRH, which like nafarelin acetate contains only a single amino acid substitution (D-Trp6 for Gly6) when compared to the natural hormone. In the treatment of advanced prostate cancer, it is important to reduce serum testosterone levels to very low levels, which can be achieved surgically by orchiectomy. When this surgical method is unacceptable to the patient, an alternative approach is “chemical castration,” which can be achieved by use of estrogen therapy, leuprolide,goserelin or histrelin acetates, and now, triptorelin pamoate. This product is available for IM depot injection (monthly or every 3 months), wherein serum testosterone concentration drops to a level generally seen in surgically castrated men.부작용
The side effects of Triptorelin: Painful or difficult urination, burning when you urinate, blood in the urine; bone pain; (in children) new or worsening signs of puberty; a seizure; chest pain or pressure, pain spreading to your jaw or shoulder; sudden numbness or weakness, slurred speech; increased pressure inside the skull - severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; loss of movement in any part of your body; high blood sugar - increased thirst, increased urination, hunger, dry mouth, fruity breath odor; or nerve problems - back pain, muscle weakness, problems with balance or coordination, severe numbness or tingling in your legs or feet, loss of bladder or bowel control.Triptorelin 준비 용품 및 원자재
원자재
준비 용품
Triptorelin 공급 업체
글로벌( 342)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 |
info@cellmano.com | China | 999 | 58 |
Apextide Co Ltd | +undefined15700198315 |
senjie.hou@sinopep.com | China | 71 | 58 |
Hebei Anlijie Biotechnology Co., Ltd | +8619031013551 |
ably@aljbio.com | China | 196 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 971 | 58 |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 3001 | 58 |
Apeloa production Co.,Limited | +8619933239880 |
admin@apcl.com.cn | China | 341 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 |
asdf@shanghaihg.cn | China | 265 | 58 |
qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 |
cui56813@163.com | China | 110 | 58 |
Triptorelin 관련 검색:
Triptorelin acetate
Vasopressin
Abarelix
FERTIRELIN
Octreotide
Leuprorelin
(D-LEU7)-TRIPTORELIN
(TRP6)-TRIPTORELIN
(D-TYR5)-TRIPTORELIN
[D-TRP6]-LH-RH-LEU-ARG-PRO-GLY-NH2 TRIPTORELIN-LEU-ARG-PRO-GLY AMIDE,(D-SER4)-TRIPTORELIN
(DES-PYR1)-TRIPTORELIN
[D-TRP6]-LHRH FRAGMENT, 1-6 TRIPTORELIN 1-6 AMIDE,TRIPTORELIN (1-6) AMIDE
FORMYL-TRIPTORELIN (2-10)
(D-HIS2)-TRIPTORELIN
TRIPTORELIN (FREE ACID)
TRIPTORELIN-LEU-ARG-PRO-GLY AMIDE
Triptorelin
GLP-HIS-TRP-SER-TYR-DTRP-LEU-ARG-PRO-GLY-NHET