레목시프리드

레목시프리드
레목시프리드 구조식 이미지
카스 번호:
80125-14-0
한글명:
레목시프리드
동의어(한글):
레목시프리드
상품명:
Remoxipride
동의어(영문):
Roxiam;FLA-731;A-33547;REMOXIPRIDE;(S)-Remoxipride;Remoxipride [USAN:BAN:INN];(S)-3-Bromo-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2,6-dimethoxybenzamide;(S)-3-BroMo-N-((1-ethylpyrrolidin-2-yl)Methyl)-2,6-diMethoxybenzaMide;3-Bromo-2,6-dimethoxy-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]benzamide;3-Bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxybenzamide
CBNumber:
CB2493967
분자식:
C16H23BrN2O3
포뮬러 무게:
371.27
MOL 파일:
80125-14-0.mol

레목시프리드 속성

알파
D20 -64° (c = 2 in ethanol)
끓는 점
439.9±45.0 °C(Predicted)
밀도
1.292
저장 조건
2-8°C
산도 계수 (pKa)
pKa 8.9 (Uncertain)
CAS 데이터베이스
80125-14-0(CAS DataBase Reference)
NIST
Remoxipride(80125-14-0)

안전

레목시프리드 C화학적 특성, 용도, 생산

용도

Antipsychotic.

일반 설명

Remoxipride is a D2 receptorblocker.It is as effective as haloperidol with fewer EPS andautonomic side effects. Negative symptoms of schizophreniaare diminished. The drug is classed as an atypical antipsychotic.Life-threatening aplastic anemia was reported with itsuse, which prompted its withdrawal from the market.
With respect to the atypical antipsychotics, two eventslong in the past may shed some light on the events of today.
The field of reuptake-inhibiting antidepressants arose whenonly a very small structural change was made in an antipsychoticdrug, and the new activity noted. (The antipsychoticactivity remained.) Therefore, small changes in structurecan produce antipsychotics that are active against depressivesymptoms. Likewise, small changes in structure could provideselectivity among D2 receptors.

레목시프리드 준비 용품 및 원자재

원자재

준비 용품


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