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NFPA 704
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4
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2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole C화학적 특성, 용도, 생산
용도
Neurodazine induces neurogenesis in mature skeletal muscle cells, via non-pluripotent C2C12 myoblasts.
일반 설명
A cell-permeable trisubstituted imidazole compound that induces neurogenesis of non-pluripotent C2C12 myoblasts as well as cells derived from mature human skeletal muscle cultures (2 μM for 7-10 days). Shown to preferentially upregulate genes involved in neurogenesis, but not those pertaining to myogenesis, in C2C12 myoblasts.
Biochem/physiol Actions
Neurodazine is a promoter of neurogenesis. It induces a generation of new nerve cells from skeletal muscle fibers both immature, differentiated myotubes and mature skeletal muscle. Neurodazine promotes the expression of neuron-specific markers in treated C2C12 cells (neurogenesis). In addition, in conjunction with a microtubule-destabilizing agent, Neurodazine allows neurogenic conversion of both differentiated immature myotubes and mature skeletal muscle. Neurodazine is a potential alternative approach to using stem cells.
2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole 준비 용품 및 원자재
원자재
준비 용품
2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole 공급 업체
