1H-테트라졸
|
|
1H-테트라졸 속성
- 녹는점
- 156-158°C
- 끓는 점
- 220℃
- 밀도
- 0.798 g/mL at 20 °C
- 굴절률
- n
20/D 1.348
- RTECS 번호
- UW7370000
- 인화점
- 5 °C
- 저장 조건
- Room temperature.
- 용해도
- DMSO및메탄올에 용해됨
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 4.9(at 25℃)
- 색상
- 크림부터 오렌지까지
- 수용성
- 녹는
- 분해온도
- 220°C
- BRN
- 105799
- 안정성
- RT에서 안정적
- InChIKey
- KJUGUADJHNHALS-UHFFFAOYSA-N
- CAS 데이터베이스
- 288-94-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | F,Xn,E | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 11-20/21/22-36-5-4 | ||
| 안전지침서 | 16-26-36-36/37-35-15 | ||
| 유엔번호(UN No.) | UN 1993 3/PG 2 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 3-4.15-10 | ||
| 위험 등급 | 4.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29339900 | ||
| 기존화학 물질 | KE-33715 |
| 그림문자(GHS): |
 
|
|||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 신호 어: | Danger | |||||||||||||||||||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
|
|||||||||||||||||||||||||||||||||||||||||||||||||
| 예방조치문구: |
|
1H-테트라졸 C화학적 특성, 용도, 생산
화학적 성질
white crystals or crystalline powder용도
Tetrazole is a catalyst for phosphoramidite synthesis. It is also used as an intermediate for the drug cilostazol. Cilostazol is an antiplatelet drug and a vasodilator. Tetrazole derivatives are used as antibiotics and optically active tetrazole-containing antifungal preparations of azole type was reported.제조 방법
The first tetrazole synthesis was reported in 1885.Tetrazole Synthesis: Nano-TiCl4.SiO2 (0.1 g) was added to a mixture of benzonitrile (1 mmol), sodium azide (2 mmol) in DMF (5 mL) at reflux for 2 h. After completion of reaction (as monitored by TLC), the mixture was allowed to cool to room temperature, the catalyst was removed by filtration. Then by adding ice water and 4N HCl (5 mL) to the residue, a white solid was obtained. This was then washed with cold chloroform. This simple procedure yielded pure tetrazole with good yields.
정의
ChEBI: 1H-tetrazole is a tetrazole tautomer where the proton is located on the 1st position. It is a tetrazole and a one-carbon compound. It is a tautomer of a 2H-tetrazole and a 5H-tetrazole.주요 응용
1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.일반 설명
Tetrazole is an odorless white to light-yellow crystalline powder. Mp:1 55-157°C. When heated to decomposition Tetrazole emits toxic oxides of nitrogen fumes. Can explode if exposed to shock or heat from friction or fire. The primary hazard is from blast effect where the entire load can explode instantaneously and not from flying projectiles and fragments.건강위험
Fire may produce irritating, corrosive and/or toxic gases.화재위험
MAY EXPLODE AND THROW FRAGMENTS 1600 meters (1 MILE) OR MORE IF FIRE REACHES CARGO.Purification Methods
Crystallise the tetrazole from EtOH and sublime it under high vacuum at ca 120o (care should be taken due to possible EXPLOSION). [Beilstein 26 H 346, 26 I 108, 26 II 196, 26 III/IV 1652.]1H-테트라졸 준비 용품 및 원자재
원자재
준비 용품
1H-테트라졸 공급 업체
글로벌( 569)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 |
info@allgreenchem.com | China | 5986 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12468 | 58 |
| XINXIANG RUNYU MATERIAL CO., LTD. | +86-13592593621; +8613592593621 |
sales@runvmat.com | China | 424 | 58 |
| Shandong Juchuang Chemical Co., LTD | +undefined15030412209 |
admin@juchuangchem.com | China | 387 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9341 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
1H-테트라졸 관련 검색:
5-페닐-1H-테트라졸 염화 2,3,5-트리페닐 테트라졸륨 니트로 BT 5-머캅토-1-메틸테트라졸 1-[2-(다이메틸아미노)에틸]-1,2-다이하이드로-5H-테트라졸-5 -티온 1-페닐-1H-테트라졸-5-티올 1H-테트라졸
1H-Tetrazole-1-acetic acid
5-(2,4-DICHLOROPHENYL)-1H-TETRAZOLE,5-(2,4-DICHLOROPHENYL)-1H-TETRAZOLE,5-(2,4-DICHLOROPHENYL)-1H-TETRAZOLE
5-(2,6-DICHLOROPHENYL)-1H-TETRAZOLE,5-(2,6-DICHLOROPHENYL)-1H-TETRAZOLE
5-(2,5-DICHLOROPHENYL)-1H-TETRAZOLE,5-(2,5-DICHLOROPHENYL)-1H-TETRAZOLE
1-(M-SULFOPHENYL)-5-MERCAPTO-1H-TETRAZOLE SODIUM SALT
5-(2,3-DICHLOROPHENYL)-1H-TETRAZOLE,5-(2,3-DICHLOROPHENYL)TETRAZOLE,5-(2,3-DICHLOROPHENYL)-1H-TETRAZOLE,5-(2,3-DICHLOROPHENYL)TETRAZOLE
5-Mercapto-1H-tetrazole-1-methanesulfonic acid disodium salt
1H-TETRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER SODIUM SALT
5-(Methylthio)-1H-tetrazole
5-(2,6-DIFLUOROPHENYL)TETRAZOLE,5-(2,6-DIFLUOROPHENYL)TETRAZOLE
5-[2-(4-CHLORO-3,5-DIMETHYL-PYRAZOL-1-YL)-ETHYL]-2H-TETRAZOLE,5-[2-(4-CHLORO-3,5-DIMETHYL-PYRAZOL-1-YL)-ETHYL]-2H-TETRAZOLE