세틸 알코올
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세틸 알코올 속성
- 녹는점
- 48-50 °C (lit.)
- 끓는 점
- 179-181 °C/10 mmHg (lit.)
- 밀도
- 0.818 g/mL at 25 °C (lit.)
- 증기 밀도
- 8.34 (vs air)
- 증기압
- <0.01 mm Hg ( 43 °C)
- 굴절률
- nD79 1.4283
- FEMA
- 2554 | 1-HEXADECANOL
- 인화점
- 275 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 알코올, 클로로포름, 에테르에 용해됨
- 물리적 상태
- 분말, 플레이크 또는 펠렛
- 산도 계수 (pKa)
- 15.20±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
- 냄새
- 100.00%에서. 왁스 같은 깨끗한 기름기 많은 꽃 기름진
- ?? ??
- 밀랍같은
- 폭발한계
- 8%
- 수용성
- 불용성
- Merck
- 14,2028
- JECFA Number
- 114
- BRN
- 1748475
- Dielectric constant
- 3.6(60℃)
- 안정성
- 안정적인. 강한 산화제, 강산과 호환되지 않습니다.
- LogP
- 6.7
- CAS 데이터베이스
- 36653-82-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 38-36/37/38 | ||
안전지침서 | 22-24/25-37 | ||
WGK 독일 | - | ||
RTECS 번호 | MM0225000 | ||
자연 발화 온도 | 483 °F | ||
TSCA | Yes | ||
HS 번호 | 29051700 | ||
유해 물질 데이터 | 36653-82-4(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg | ||
기존화학 물질 | KE-18460 |
세틸 알코올 C화학적 특성, 용도, 생산
개요
1-Hexadecanol is a waxy white powder or flake form at room temperature, and is insoluble in water and soluble in alcohols and oils. Discovered by Chevrenl in 1913, It is one of the oldest known long-chain alcohol. It can be produced from the reduction of palmitic acid. 1-Hexadecanol may be contained in cosmetic and personal care products such as shampoos, creams and lotions. it is mainly used as an opacifier, emulsifier, and thickening agent that alter the thickness of the liquid, and increase and stabilize the foaming capacity.화학적 성질
Cetyl alcohol occurs as waxy, white flakes, granules, cubes, or castings. It has a faint characteristic odor and bland taste.출처
Reported as a major constituent of spermaceti oil, where it is present chiefy as cetyl palmitate Also reported found in guava, peach, pear, kohlrabi, baked potato, mustard, Parmesan cheese, butter, milk powder, boiled egg, cooked chicken, roasted beef, beef fat, whiskies, tea, starfruit, mango, rice, licorice, kiwifruit, loquat, endive, shrimp, crab, clam, Cape gooseberry and pawpaw용도
1-Hexadecanol has been used in preparation of:(±)-2-methoxyheptadecanoic acid (fatty acid)
high-chain fatty acid esters of 1-hexadecanol, novel organic phase change material for thermal energy storage
hexadecane (alkane) in the presence of membrane fraction of Vibrio furnissii M1
생산 방법
Cetyl alcohol may be manufactured by a number of methods such as esterification and hydrogenolysis of fatty acids or by catalytic hydrogenation of the triglycerides obtained from coconut oil or tallow. Cetyl alcohol may be purified by crystallization and distillation.정의
ChEBI: 1-Hexadecanol is a long chain fatty alcohol that is hexadecane substituted by a hydroxy group at position 1. It is a synthetic, solid, fatty alcohol and nonionic surfactant. It is used as an emulsifying agent in pharmaceutical preparations.일반 설명
1-Hexadecanol is a free fatty acid alcohol generally used as an emulsifier, emollient, opacifier and surfactant in cosmetics formulations.Safety
Cetyl alcohol is mainly used in topical formulations, although it has also been used in oral and rectal preparations.Cetyl alcohol has been associated with allergic delayed-type hypersensitivity reactions in patients with stasis dermatitis. Crosssensitization with cetostearyl alcohol, lanolin, and stearyl alcohol has also been reported. It has been suggested that hypersensitivity may be caused by impurities in commercial grades of cetyl alcohol since highly refined cetyl alcohol (99.5%) has not been associated with hypersensitivity reactions.
LD50 (mouse, IP): 1.6 g/kg
LD50 (mouse, oral): 3.2 g/kg
LD50 (rat, IP): 1.6 g/kg
LD50 (rat, oral): 5 g/kg
저장
Cetyl alcohol is stable in the presence of acids, alkalis, light, and air; it does not become rancid. It should be stored in a well-closed container in a cool, dry place.Purification Methods
Crystallise the alcohol from aqueous EtOH or from cyclohexane. Alternatively purify it by zone refining. The purity can be checked by gas chromatography. [Beilstein 1 H 429, 1 I 219, 1 II 466, 1 III 1815, 1 IV 1876.]비 호환성
Incompatible with strong oxidizing agents. Cetyl alcohol is responsible for lowering the melting point of ibuprofen, which results in sticking tendencies during the process of film coating ibuprofen crystals.Regulatory Status
Included in the FDA Inactive Ingredients Database (ophthalmic preparations, oral capsules and tablets, otic and rectal preparations, topical aerosols, creams, emulsions, ointments and solutions, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Nonmedicinal Ingredients.세틸 알코올 준비 용품 및 원자재
원자재
Chemicals
Chromatographic fixative
나트륨 붕소수화물
수산화나트륨
Detergent
세틸 팔미트산염
Palmitoyl chloride
중탄산나트륨(중조)
염산
산화칼슘(생석회)
16-헨트리아콘타논
준비 용품
세틸 알코올 공급 업체
글로벌( 564)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd | 510-85010237 |
overseamarketing@alphahi-tech.com | CHINA | 41 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 |
daisy@crovellbio.com | China | 5956 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 |
cherry@crovellbio.com | China | 18452 | 58 |
Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 |
admin@china-yime.com | China | 563 | 58 |
Shandong Dexiang International Trade Co., Ltd | 15662695772;+8615662691337 |
sales006@dexiangchemical.com | China | 998 | 58 |
Hebei Mojin Biotechnology Co.,Ltd | +8613288715578 |
angelia@hbmojin.com | China | 320 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |