4'-브로모아세트아닐리드
|
|
4'-브로모아세트아닐리드 속성
- 녹는점
- 165-169 °C(lit.)
- 끓는 점
- 353.4°C (estimate)
- 밀도
- 1.72
- 굴절률
- 1.6120 (estimate)
- 저장 조건
- Store below +30°C.
- 용해도
- 알코올: 적당히 용해됨
- 물리적 상태
- 결정질 분말 또는 결정
- 산도 계수 (pKa)
- 14.25±0.70(Predicted)
- 색상
- 흰색에서 베이지색 또는 밝은 회색
- 수용성
- 불용성
- Merck
- 14,1399
- BRN
- 2208091
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- CAS 데이터베이스
- 103-88-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36 | ||
| 유엔번호(UN No.) | 2811 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | AD9625000 | ||
| 위험 참고 사항 | Irritant | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1(b) | ||
| 포장분류 | III | ||
| HS 번호 | 29242998 | ||
| 독성 | mouse,LD50,intraperitoneal,250mg/kg (250mg/kg),National Technical Information Service. Vol. AD277-689, | ||
| 기존화학 물질 | KE-03702 |
4'-브로모아세트아닐리드 C화학적 특성, 용도, 생산
화학적 성질
4'-Bromoacetanilide is a white to light beige crystalline solid with a melting point of 168°C and a relative density of 1.717. It is soluble in benzene, chloroform, and ethyl acetate, slightly soluble in alcohol and hot water, and insoluble in cold water. This compound can be prepared by brominating acetanilide and is commonly used as an intermediate in organic synthesis.용도
4'-Bromoacetanilide is used as an internal standard for phenylurea and the respective metabolic products in oysters. It has also been used as a reagent in the production of a new ligand to form a coordination compex between gadolinium(III) and T=titanium(IV) oxide. It was used in the synthesis of new ligand for anchoring Gd(III) chelates onto TiO2 surface.제조 방법
Preparation of 4'-Bromoacetanilide from Acetanilide.Principle: Aromatic compounds can be conveniently brominated by the use of brominating agent, which is normally a solution of bromine in acetic acid. Bromination of activated aromatic compounds usually give 2, 4, 6-tribromo derivatives while moderately activating group like anilide give preferably the para bromo product.
Reaction:
Procedure: Dissolve 0.5 g acetanilide in 0.6 ml glacial acetic acid and add 2.5 ml bromine solution in acetic acid (25% w/v). Shake the mixture for 1 h. After 1 h, pour the mixture on to crushed ice (20 g) with stirring. Filter the separated product and wash with cold water. Dry the product, record the practical yield and re-crystallize it.
Re-crystallization: Dissolve the crude product in minimum amount of ethyl alcohol in a beaker by heating on a water bath. Filter the hot solution and cool the filtrate. The crystals of the product separate out. Filter, dry and record the melting point and TLC (using toluene as a solvent).
Purification Methods
Crystallise the anilide from aqueous MeOH or EtOH. Purify it by zone refining. [Beilstein 12 IV 1504.]4'-브로모아세트아닐리드 준비 용품 및 원자재
원자재
준비 용품
4'-브로모아세트아닐리드 공급 업체
글로벌( 281)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15954 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21687 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
| Richest Group Ltd | 18017061086 |
oled@richest-group.com | CHINA | 5601 | 58 |
| SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34571 | 58 |
4'-브로모아세트아닐리드 관련 검색:
4-브로모아닐린 N-(4-메틸페닐)아세트아미드 p-아미노아세트아닐리드 아세트아마이드 모노브로모초산 브롬화물 아세트아닐리드 브로모벤젠
2-BENZOYLACETANILIDE
2-Bromoaniline
4'-Nitroacetanilide
5-Bromoisatin
N-(4-BROMO-2-METHYLPHENYL)MALEAMIC ACID
N-(4-BROMOPHENYL)-2-CHLOROACETAMIDE
4'-BROMO-2'-NITROACETANILIDE
N-Methyl-2-bromoacetanilide,N-Methyl-2-bromoacetanilide
2-METHYL-4-BROMOACETANILIDE,2-METHYL-4-BROMOACETANILIDE
4-Acetyl-2-bromoacetanilide,4-Acetyl-2-bromoacetanilide
m-bromoacetanilid