Scutellarin
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Scutellarin 속성
- 녹는점
- 300～301℃
- 끓는 점
- 891.6±65.0 °C(Predicted)
- 밀도
- 1.810±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,2-8°C
- 용해도
- DMSO(약간), 메탄올(매우 소량, 초음파 처리)에 용해됨
- 산도 계수 (pKa)
- 2.72±0.70(Predicted)
- 색상
- 밝은 노란색에서 노란색까지
- BRN
- 71779
- CAS 데이터베이스
- 27740-01-8(CAS DataBase Reference)
안전
| 안전지침서 | 24/25 | ||
|---|---|---|---|
| WGK 독일 | 3 | ||
| HS 번호 | 29389090 |
Scutellarin C화학적 특성, 용도, 생산
개요
Scutellarin is a flavone that has been found in S. barbata and has diverse biological activities, including anticancer, lipid lowering, antioxidative, and neurocognitive properties. It inhibits proliferation of PC-9 and H1975 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner and induces apoptosis and autophagy when used at a concentration of 160 μM, effects that can be blocked by the autophagy inhibitor HCQ . Scutellarin (30 and 60 mg/kg per day) reduces tumor growth in an H1975 mouse xenograft model. It decreases serum total cholesterol and LDL-cholesterol and increases HDL-cholesterol in a high-fat diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD) when administered at doses of 25 and 50 mg/kg. It decreases hepatic malondialdehyde (MDA), glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvic transaminase (GPT) activity, increases catalase (CAT) and total antioxidative capacity (T-AOC) activity, and increases the hepatic expression of PPARγ, PGC-1α, and Nrf2 in the same model. Scutellarin (5, 25, and 50 mg/kg per day) also prevents deficits in spatial and novel object memory in rats in the Y maze and novel object recognition test, respectively.정의
ChEBI: The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein.Scutellarin 준비 용품 및 원자재
원자재
4',5,6,7-Tetrahydroxyflavone tetraacetate
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
SCUTELLAREIN
scutellarin Methylester
준비 용품
Scutellarin 공급 업체
글로벌( 276)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 2113 | 58 |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 |
clara@hbshengyang.com | China | 783 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 |
sale02@cqherb.com | CHINA | 376 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
Scutellarin 관련 검색:
바이칼린 바이칼레인 게니스틴 플라본 바이칼린 하이드레이트
Isoimperatorin
Isoliquiritigenin
5,7-Dihydrox -4'-methoxyisoflavone
SCUTELLAREIN
APIGENIN-7-GLUCURONIDE
Wogonoside
Tetramethyl-O-scutellarin
3',5'-Dimethoxytricetin 7-O-β-D-glucopypranoside
7-HYDROXYFLAVONE-BETA-D-GLUCOSIDE
BREVISCAPIN
Scutellarin
ERIGERON BREVISCAPUS SCUTELLARIN:>5%,DCQ:>5%