4-Methylpyridin-2-amine

4-Methylpyridin-2-amine 구조식 이미지
카스 번호:
695-34-1
상품명:
4-Methylpyridin-2-amine
동의어(영문):
2-AMINO-4-METHYLPYRIDINE;2-AMINO-4-PICOLINE;Aminopicoline;w45;W 45;4M2AP;ra1226;RA 1226;NSC 1490;NSC 6972
CBNumber:
CB9854129
분자식:
C6H8N2
포뮬러 무게:
108.14
MOL 파일:
695-34-1.mol
MSDS 파일:
SDS

4-Methylpyridin-2-amine 속성

녹는점
96-99 °C (lit.)
끓는 점
230 °C (lit.)
밀도
1.0275 (estimate)
증기압
3.71Pa at 25℃
굴절률
1.5560 (estimate)
인화점
118 °C
저장 조건
Keep in dark place,Inert atmosphere,Room temperature
용해도
DMF: 자유롭게 용해됨
물리적 상태
플레이크
산도 계수 (pKa)
pK1: 7.48(+1) (25°C)
색상
약간 노란색에서 베이지색 또는 갈색
수용성
녹는
감도
Hygroscopic
Merck
14,466
BRN
107066
LogP
0.56-1.08
CAS 데이터베이스
695-34-1(CAS DataBase Reference)
NIST
2-Pyridinamine, 4-methyl-(695-34-1)
EPA
2-Pyridinamine, 4-methyl- (695-34-1)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 45-46-60-61-8-21-25-26-34-42/43-48/23-50/53-36/37/38-33-23/24/25
안전지침서 53-45-60-61-37/39-28A-26-36/37/39
유엔번호(UN No.) UN 3086 6.1/PG 1
WGK 독일 3
RTECS 번호 TJ5150000
TSCA Yes
위험 등급 6.1
포장분류 II
HS 번호 29333999
독성 LD50 oral in rat: 200mg/kg
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H373 장기간 또는 반복 노출되면 장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킬 수 있음 특정 표적장기 독성 - 반복 노출 구분 2 경고 P260, P314, P501
예방조치문구:
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P314 불편함을 느끼면 의학적인 조치·조언을 구하시오.
NFPA 704
1
3 1

4-Methylpyridin-2-amine MSDS


4-Methylpyridin-2-amine

4-Methylpyridin-2-amine C화학적 특성, 용도, 생산

화학적 성질

Light yellow to brown flakes

용도

Intermediate, medicine.

일반 설명

2-Amino-4-methylpyridine acts as ligand and forms methoxo-bridged copper(II) complexes.

Synthesis

A mixture of 2-amino-3-chloro-4-methylpyridine 0.96 g (0. 0067πο1) and benzoic acid, 1.83 g (0.015 mol) was added, the copper powder was added, reacted at 150 ° C for 1 h, and the reaction solution was added to water, Adding the decolorizer, adjusting the pH of the filtered solution to pH 9, filtering and drying the filter cake to obtain 0.65 g of crude 4-Methylpyridin-2-amine as a yellow solid, the yield was 89.3percent. The crude 0.65g dissolved in dilute hydrochloric acid solution to the crude product completely dissolved to obtain a salt solution, adding ethyl acetate to the salt solution to extract the water phase, slowly adding sodium bicarbonate to the aqueous phase Solution to pH 9, the solid was completely precipitated, filtered, and the filtrate was washed with distilled water and dried in vacuo to give 0.53 g of 4-Methylpyridin-2-amine as a pale yellow solid.

Purification Methods

Crystallise it from EtOH or a 2:1 *benzene/acetone mixture, and dry it under vacuum as in the prevous entry. [Beilstein 22/9 V 325.]

4-Methylpyridin-2-amine 준비 용품 및 원자재

원자재

준비 용품


4-Methylpyridin-2-amine 공급 업체

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